Journal article
Pregnancy and severe influenza infection in the 2013-2014 influenza season
Obstetrics and gynecology (New York. 1953), Vol.125(1), pp.184-192
01/01/2015
DOI: 10.1097/AOG.0000000000000593
PMID: 25560123
Abstract
OBJECTIVETo describe the epidemiologic and clinical characteristics of critically ill pregnant and postpartum women with influenza infection reported in the 2013-2014 season. METHODSThe California Department of Public Health conducts surveillance for patients with laboratory-confirmed influenza who die or require hospitalization in intensive care units. For this case series, we reviewed data on pregnant and postpartum (6 weeks or less from delivery) women reported in the 2013-2014 influenza season. RESULTSFrom September 29, 2013, through May 17, 2014, 17 pregnant women with severe influenza were reported. The median age was 29 years (range 17-44 years). Sixteen (94%) were in the second or third trimester. Fifteen (88%) patients were hospitalized, nine (53%) required mechanical ventilation, five (29%) required emergent cesarean delivery, and four (24%) died. Of 14 patients with available information, only two (14%) received influenza vaccination during pregnancy. Seven patients who tested positive by polymerase chain reaction also had rapid influenza diagnostic testing performed; only one (14%) had a positive rapid influenza diagnostic test results. Fifteen patients received antiviral treatment; four (27%) began treatment within 48 hours of symptom onset. One additional patient was 36 days postpartum and required intensive care unit admission and mechanical ventilation for influenza-associated acute respiratory distress syndrome. CONCLUSIONInfluenza remains a significant cause of morbidity and mortality in pregnant and postpartum women; in our series, a majority were not vaccinated. During the influenza season, pregnant women with suspected influenza should receive prompt empiric antiviral therapy, regardless of rapid influenza diagnostic test results or vaccination status. LEVEL OF EVIDENCEIII.
Details
- Title: Subtitle
- Pregnancy and severe influenza infection in the 2013-2014 influenza season
- Creators
- Janice K Louie - National Center for Chronic Disease Prevention and Health PromotionCatheryn J Salibay - National Center for Chronic Disease Prevention and Health PromotionMonica KangRose E Glenn-FinerErin L MurrayDenise J Jamieson
- Resource Type
- Journal article
- Publication Details
- Obstetrics and gynecology (New York. 1953), Vol.125(1), pp.184-192
- DOI
- 10.1097/AOG.0000000000000593
- PMID
- 25560123
- ISSN
- 1873-233X
- eISSN
- 1873-233X
- Language
- English
- Date published
- 01/01/2015
- Academic Unit
- Obstetrics and Gynecology; VPMA - Administration
- Record Identifier
- 9984446460002771
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