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Preoptic-hypothalamic periventricular lesions: Impairment of thirst-motivated behavior
Journal article   Peer reviewed

Preoptic-hypothalamic periventricular lesions: Impairment of thirst-motivated behavior

Steven L Bealer and Alan Kim Johnson
Physiology & behavior, Vol.22(5), pp.841-846
1979
DOI: 10.1016/0031-9384(79)90325-1
PMID: 504392

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Abstract

To assess the effect of anteroventral third ventricle (AV3V) lesions on thirst-motivated behavior in the rat, the intake of quinine hydrochloride (QHCl) solutions and of QHCl-adulterated food was evaluated. Two-bottle choice tests were also administered to determine if lesions altered the rejection threshold for QHCl solutions. AV3V ablation significantly reduced QHCl solution intake in a one-bottle test, but did not alter the two-bottle preference relationships. Ingestion of QHCl-adulterated food was slightly reduced only if the animals had no prior experience with the taste of QHCl. These findings suggest that AV3V ablation produces deficits in thirst-motivated behavior, and that AV3V periventricular tissue contains elements necessary for the elaboration of normal thirst.
Anteroventral third ventricle (AV3V) Drinking behavior Feeding behavior Periventricular Taste

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