Journal article
Preparation of aromatic farnesol analogues via a Cu(I)-mediated Grignard coupling of THP ethers
Tetrahedron letters, Vol.39(8), pp.783-786
1998
DOI: 10.1016/S0040-4039(97)10610-4
Abstract
A Cu(I)-mediated reaction of aromatic Grignard reagents with allylic tetrahydropyranyl ethers results in formation of the coupled products in good yields. This methodology allows facile synthetic manipulation of compounds with two reactive allylic positions. Allylic tetrahydropyranyl (THce:simple-para) ethers undergo facile reaction with aryl Grignard reagents in a Cu(I)-mediated coupling. [Display omitted]
Details
- Title: Subtitle
- Preparation of aromatic farnesol analogues via a Cu(I)-mediated Grignard coupling of THP ethers
- Creators
- Mark F MechelkeDavid F Wiemer
- Resource Type
- Journal article
- Publication Details
- Tetrahedron letters, Vol.39(8), pp.783-786
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/S0040-4039(97)10610-4
- ISSN
- 0040-4039
- eISSN
- 1873-3581
- Language
- English
- Date published
- 1998
- Academic Unit
- Chemistry; Neuroscience and Pharmacology
- Record Identifier
- 9983985989902771
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