Journal article
Preparative purification of tyrosinamide N-linked oligosaccharides
Journal of chromatography. A, Vol.720(1-2), pp.235-249
01/12/1996
DOI: 10.1016/0021-9673(95)00458-0
PMID: 8601193
Abstract
N-linked oligosaccharides from glycoproteins can be either analyzed on a sub-nanomole scale or preparatively purified on a multi-micromole scale. Each goal necessitates a unique analytical strategy often involving oligosaccharide derivatization to enhance separation and detection. Tyrosinamide-oligosaccharides were developed to facilitate the preparative purification of N-linked oligosaccharides. These have found many uses in oligosaccharide remodeling, in the preparation of neoglycoconjugates, in developing receptor probes, and even as analytical standards in chromatography. This review discusses progress in the preparation of tyrosinamide-oligosaccharides from different glycoproteins and their utility in glycobiology research.
Details
- Title: Subtitle
- Preparative purification of tyrosinamide N-linked oligosaccharides
- Creators
- K G Rice - Division of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, Ohio State University, Columbus 43210, USAM L Corradi Da Silva
- Resource Type
- Journal article
- Publication Details
- Journal of chromatography. A, Vol.720(1-2), pp.235-249
- DOI
- 10.1016/0021-9673(95)00458-0
- PMID
- 8601193
- NLM abbreviation
- J Chromatogr A
- ISSN
- 0021-9673
- Publisher
- Netherlands
- Grant note
- DK45742 / NIDDK NIH HHS GM48048 / NIGMS NIH HHS
- Language
- English
- Date published
- 01/12/1996
- Academic Unit
- Pharmaceutical Sciences and Experimental Therapeutics; Craniofacial Anomalies Research Center; Medicinal and Natural Products Chemistry
- Record Identifier
- 9984065324102771
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