Journal article
Presence of a left common pulmonary vein and pulmonary vein anatomical characteristics as predictors of outcome following cryoballoon ablation for paroxysmal atrial fibrillation
Journal of interventional cardiac electrophysiology, Vol.62(2), pp.409-417
11/01/2021
DOI: 10.1007/s10840-020-00916-6
PMID: 33206281
Abstract
Purpose Pulmonary vein (PV) isolation using cryoballoon ablation (CBA) is a common therapy for patients with drug-refractory paroxysmal atrial fibrillation (PAF). However, initial CBA is successful in only 70-80% of patients. The role of an atypical left common PV (LCPV) and PV anatomical indices on CBA outcomes remains unclear. Methods We followed 80 patients (age 60.7 +/- 9.7, 31 % women) with PAF undergoing CBA for 1-year post-procedure for the development of recurrent atrial arrhythmias (AA). Recurrence was assessed by documented AA on EKG or any form of long-term cardiac rhythm monitoring. The presence of an LCPV and individual PV diameters were evaluated using cardiac CT. Based on the maximum and minimum PV ostial diameters, the eccentricity index (EI), ovality index (OI), and PV ostial area (PVA) were calculated for all the veins. A multivariable Cox-proportional hazard model assessed whether the presence of an LCPV or PV anatomic indices (EI, OI, and PVA) predicted recurrence of AA following CBA. Results After 1-year follow-up, 19 (23.7%) participants developed recurrence of AA. On multivariable regression, the presence of an LCPV did not predict the recurrence of AA (p = 0.38). Among the PV anatomical indices, on univariate analysis, only the area of the left inferior PV showed a trend towards predicting recurrence, though this result was not significant on multivariate analysis (p = 0.09). Conclusions In patients with PAF, neither the presence of an LCPV nor individual PV anatomical indices predicted recurrence of AA following CBA.
Details
- Title: Subtitle
- Presence of a left common pulmonary vein and pulmonary vein anatomical characteristics as predictors of outcome following cryoballoon ablation for paroxysmal atrial fibrillation
- Creators
- Abhishek Bose - St Vincent HospitalParag A. Chevli - Wake Forest UniversityGregory Berberian - Saint Vincent HospitalJerzy Januszkiewicz - Saint Vincent HospitalGhasan Ahmad - University of Maryland, BaltimoreZeba Hashmath - Saint Vincent HospitalAjay K. Mishra - Saint Vincent HospitalDouglas Laidlaw - Saint Vincent Hospital
- Resource Type
- Journal article
- Publication Details
- Journal of interventional cardiac electrophysiology, Vol.62(2), pp.409-417
- DOI
- 10.1007/s10840-020-00916-6
- PMID
- 33206281
- NLM abbreviation
- J Interv Card Electrophysiol
- ISSN
- 1383-875X
- eISSN
- 1572-8595
- Publisher
- Springer Nature
- Number of pages
- 9
- Language
- English
- Date published
- 11/01/2021
- Academic Unit
- Internal Medicine
- Record Identifier
- 9985221147902771
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