Journal article
Presence of wax esters and squalene in human saliva
Archives of oral biology, Vol.56(6), pp.588-591
06/2011
DOI: 10.1016/j.archoralbio.2010.12.002
PMCID: PMC3095707
PMID: 21247555
Abstract
The purpose of this study was to determine the presence and relative composition of neutral lipids in human saliva.\nWhole unstimulated saliva was collected from 12 subjects ranging from 21 to 29 years old. Samples were lyophilized, and lipids were extracted using chloroform–methanol. Lipids were analysed by thin-layer chromatography.\nHuman saliva contains cholesterol, fatty acids, triglycerides, wax esters, cholesterol esters and squalene. The mean total neutral lipid content was 12.1±6.3μg/ml.\nThese lipids in human saliva closely resemble the lipids found on the skin surface. These salivary lipids are most likely produced by the sebaceous follicles in the oral mucosa and sebaceous glands associated with major salivary glands.
Details
- Title: Subtitle
- Presence of wax esters and squalene in human saliva
- Creators
- Andrew J BrasserChristopher A BarwaczDeborah V DawsonKim A BrogdenDavid R DrakePhilip W Wertz
- Resource Type
- Journal article
- Publication Details
- Archives of oral biology, Vol.56(6), pp.588-591
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/j.archoralbio.2010.12.002
- PMID
- 21247555
- PMCID
- PMC3095707
- ISSN
- 0003-9969
- eISSN
- 1879-1506
- Grant note
- DOI: 10.13039/100000002, name: National Institutes of Health; DOI: 10.13039/100000072, name: National Institute of Dental and Craniofacial Research
- Language
- English
- Date published
- 06/2011
- Academic Unit
- Oral Pathology, Radiology and Medicine; Endodontics; Biostatistics; Pediatric Dentistry; Family Dentistry; Dental Research; Periodontics
- Record Identifier
- 9984065800402771
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