Logo image
Back
Presentation and outcomes of patients with clinically T1‐2, N0 parotid mucoepidermoid carcinoma: The roles of elective neck dissection and adjuvant radiotherapy
Journal article   Open access   Peer reviewed

Presentation and outcomes of patients with clinically T1‐2, N0 parotid mucoepidermoid carcinoma: The roles of elective neck dissection and adjuvant radiotherapy

Zaid Al‐Qurayshi, Christopher Blake Sullivan, Derek B. Allison and Marisa R. Buchakjian
Head & neck, Vol.44(10), pp.2151-2161
10/2022
DOI: 10.1002/hed.27128
PMCID: PMC9544346
PMID: 35731030
Appears in  UI Libraries Support Open Access
url
https://doi.org/10.1002/hed.27128View
Published (Version of record)CC BY V4.0,  Open Access

Abstract

Objectives Examine the role of elective neck dissection (END) and adjuvant radiotherapy (RT) in early‐stage clinically N0 parotid mucoepidermoid carcinoma (MEC). Methods The study is a retrospective analysis of the National Cancer Database, 2004–2016. The study population included adult patients with MEC who underwent parotidectomy. Results A total of 1233 patients were included. Histopathology demonstrated well, moderately, and poorly differentiated MEC 47.12%, 39.98%, and 12.90% of the time, respectively. END was performed in 78.67% of patients, resulting in nodal upstaging in 4.43% and identification of extracapsular extension (ECE) in 0.72%. RT was utilized in 67.33% of patients with advanced pathological features. Neither END nor RT improved overall survival separately (p < 0.05) or combined (adjusted HR: 1.19, 95%CI: 0.52, 2.70, p = 0.68). Conclusion This study provides an epidemiological perspective regarding patients with clinically T1‐2, N0 MEC. There was no observed survival advantage with END and RT.
 Epidemiology Radiotherapy facial nerve mucoepidermoid carcinoma neck dissection parotidectomy survival UIOWA OA Agreement

Details

Metrics

6 Record Views
10 Times Cited - Web of Science
Logo image