Journal article
Presynaptic Unsilencing: Searching for a Mechanism
Neuron (Cambridge, Mass.), Vol.50(3), pp.345-346
05/04/2006
DOI: 10.1016/j.neuron.2006.04.018
PMID: 16675387
Abstract
Nascent synaptic networks have a high incidence of silent synapses. In this issue of Neuron, Shen et al. show that a brief burst of action potentials rapidly awaken silent synapses by increasing the availability of synaptic vesicles for fusion through BDNF-triggered presynaptic actin remodeling mediated by the small GTPase Cdc42.
Details
- Title: Subtitle
- Presynaptic Unsilencing: Searching for a Mechanism
- Creators
- Deniz Atasoy - Center for Basic Neuroscience, The University of Texas Southwestern Medical Center, Dallas, Texas 75390Ege T Kavalali - Center for Basic Neuroscience, The University of Texas Southwestern Medical Center, Dallas, Texas 75390
- Resource Type
- Journal article
- Publication Details
- Neuron (Cambridge, Mass.), Vol.50(3), pp.345-346
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.neuron.2006.04.018
- PMID
- 16675387
- ISSN
- 0896-6273
- eISSN
- 1097-4199
- Language
- English
- Date published
- 05/04/2006
- Academic Unit
- Iowa Neuroscience Institute; Fraternal Order of Eagles Diabetes Research Center; Neuroscience and Pharmacology
- Record Identifier
- 9984040234202771
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