Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador-Rationale, Protocol, and Phase I Results of a Population- Based Survey: An Atahualpa Project-Ancillary Study

Oscar H. Del Brutto; Mark J. Sedler; Robertino M. Mera; Pablo R. Castillo; Elizabeth H. Cusick; Jadry A. Gruen; Kelsie J. Phelan; Victor J. Del Brutto; Mauricio Zambrano; David L. Brown

doi:10.1155/2014/643589

Back

Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador-Rationale, Protocol, and Phase I Results of a Population- Based Survey: An Atahualpa Project-Ancillary Study

Journal article

Open access

Peer reviewed

Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador-Rationale, Protocol, and Phase I Results of a Population- Based Survey: An Atahualpa Project-Ancillary Study

Oscar H. Del Brutto, Mark J. Sedler, Robertino M. Mera, Pablo R. Castillo, Elizabeth H. Cusick, Jadry A. Gruen, Kelsie J. Phelan, Victor J. Del Brutto, Mauricio Zambrano and David L. Brown

International journal of vascular medicine, Vol.2014, 643589

01/01/2014

DOI: 10.1155/2014/643589

PMCID: PMC4217317

PMID: 25389500

Files and links (1)

url

https://doi.org/10.1155/2014/643589View

Published (Version of record) Open Access

Abstract

Background. Little is known on the prevalence of peripheral artery disease (PAD) in developing countries. Study design. Populationbased study in Atahualpa. In Phase I, the Edinburgh claudication questionnaire (ECQ) was used for detection of suspected symptomatic PAD; persons with a negative ECQ but a pulse pressure >= 65mmHg were suspected of asymptomatic PAD. In Phase II, the ankle-brachial index will be used to test reliability of screening instruments and to determine PAD prevalence. In Phase III, participants will be followed up to estimate the relevance of PAD as a predictor of vascular outcomes. Results. During Phase I, 665 Atahualpa residents aged >= 40 years were enrolled (mean age: 59.5 +/- 12.6 years, 58% women). A poor cardiovascular health status was noticed in 464 (70%) persons of which 27 (4%) had a stroke and 14 (2%) had ischemic heart disease. Forty-four subjects (7%) had suspected symptomatic PAD and 170 (26%) had suspected asymptomatic PAD. Individuals with suspected PAD were older, more often women, and had a worse cardiovascular profile than those with nonsuspected PAD. Conclusions. Prevalence of suspected PAD in this underserved population is high. Subsequent phases of this study will determine whether prompt detection of PAD is useful to reduce the incidence of catastrophic vascular diseases in the region.

Cardiovascular System & Cardiology

Life Sciences & Biomedicine

Peripheral Vascular Disease

Science & Technology

Details

Title: Subtitle: Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador-Rationale, Protocol, and Phase I Results of a Population- Based Survey: An Atahualpa Project-Ancillary Study
Creators: Oscar H. Del Brutto - Universidad de Especialidades Espíritu Santo
Mark J. Sedler - Stony Brook University
Robertino M. Mera - Vanderbilt University
Pablo R. Castillo - Sleep Disorders Center, Mayo Clinic College of Medicine, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Elizabeth H. Cusick - Stony Brook University
Jadry A. Gruen - Stony Brook University
Kelsie J. Phelan - Stony Brook University
Victor J. Del Brutto - Community Center, Villa Club Etapa Cosmos Mz 15 Villa 42, Atahualpa, Daule, Guayas, Ecuador.
Mauricio Zambrano - Community Center, Villa Club Etapa Cosmos Mz 15 Villa 42, Atahualpa, Daule, Guayas, Ecuador.
David L. Brown - Washington University in St. Louis
Resource Type: Journal article
Publication Details: International journal of vascular medicine, Vol.2014, 643589
DOI: 10.1155/2014/643589
PMID: 25389500
PMCID: PMC4217317
NLM abbreviation: Int J Vasc Med
ISSN: 2090-2824
eISSN: 2090-2832
Publisher: Hindawi Publishing Group
Number of pages: 8
Grant note: Universidad Espiritu Santo-Ecuador, Guayaquil-Ecuador
Language: English
Date published: 01/01/2014
Academic Unit: Dermatology
Record Identifier: 9984296215102771

Metrics

5 Record Views

4 Times Cited - Web of Science