Journal article
Prevalence and incidence of carpal tunnel syndrome in US working populations: pooled analysis of six prospective studies
Scandinavian journal of work, environment & health, Vol.39(5), pp.495-505
09/01/2013
DOI: 10.5271/sjweh.3351
PMCID: PMC4042862
PMID: 23423472
Abstract
Objectives Most studies of carpal tunnel syndrome (CTS) incidence and prevalence among workers have been limited by small sample sizes or restricted to a small subset of jobs. We established a common CTS case definition and then pooled CTS prevalence and incidence data across six prospective studies of musculoskeletal outcomes to measure CTS frequency and allow better studies of etiology.
Methods Six research groups collected prospective data at >50 workplaces including symptoms characteristic of CTS and electrodiagnostic studies (EDS) of the median and ulnar nerves across the dominant wrist. While study designs and the timing of data collection varied across groups, we were able to create a common CTS case definition incorporating both symptoms and EDS results from data that were collected in all studies.
Results At the time of enrollment, 7.8% of 4321 subjects met our case definition and were considered prevalent cases of CTS. During 8833 person-years of follow-up, an additional 204 subjects met the CTS case definition for an overall incidence rate of 2.3 CTS cases per 100 person-years.
Conclusions Both prevalent and incident CTS were common in data pooled across multiple studies and sites. The large number of incident cases in this prospective study provides adequate power for future exposure response analyses to identify work- and non-work-related risk factors for CTS. The prospective nature allows determination of the temporal relations necessary for causal inference.
Details
- Title: Subtitle
- Prevalence and incidence of carpal tunnel syndrome in US working populations: pooled analysis of six prospective studies
- Creators
- Ann Marie Dale - Washington University in St. LouisCarisa Harris-Adamson - Samuel Merritt UniversityDavid Rempel - University of California, San FranciscoFred Gerr - University of IowaKurt Hegmann - United States Department of StateBarbara Silverstein - National Institute for Occupational Safety and HealthSusan Burt - University of Wisconsin–MilwaukeeArun Garg - University of California, BerkeleyJay Kapellusch - University of California, BerkeleyLinda Merlino - University of IowaMatthew S. Thiese - United States Department of StateEllen A. EisenBradley Evanoff - Washington University in St. Louis School of Medicine
- Resource Type
- Journal article
- Publication Details
- Scandinavian journal of work, environment & health, Vol.39(5), pp.495-505
- DOI
- 10.5271/sjweh.3351
- PMID
- 23423472
- PMCID
- PMC4042862
- NLM abbreviation
- Scand J Work Environ Health
- ISSN
- 0355-3140
- eISSN
- 1795-990X
- Publisher
- Scandinavian Journal Work Environment & Health
- Number of pages
- 11
- Grant note
- UL1RR024992 / NATIONAL CENTER FOR RESEARCH RESOURCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) 5R01OH009712 / Center for Disease Control / NIOSH; United States Department of Health & Human Services; Centers for Disease Control & Prevention - USA; National Institute for Occupational Safety & Health (NIOSH) UL1 RR024992 / NIH Roadmap for Medical Research; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA UL1TR000448 / NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Advancing Translational Sciences (NCATS) National Center for Research Resources (NCRR) of the National Institutes of Health (NIH); United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) R01OH009712 / NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH; United States Department of Health & Human Services; Centers for Disease Control & Prevention - USA; National Institute for Occupational Safety & Health (NIOSH)
- Language
- English
- Date published
- 09/01/2013
- Academic Unit
- Occupational and Environmental Health; Epidemiology
- Record Identifier
- 9984363666102771
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