Journal article
Prevalence and orthopedic management of foot and ankle deformities in Charcot–Marie–Tooth disease
Muscle & nerve, Vol.57(2), pp.255-259
02/2018
DOI: 10.1002/mus.25724
PMCID: PMC5811923
PMID: 28632967
Abstract
Introduction:
Foot deformities are frequent complications in Charcot–Marie–Tooth disease (CMT) patients, often requiring orthopedic surgery. However, there are no prospective, randomized studies on surgical management, and there is variation in the approaches among centers both within and between countries.
Methods:
In this study we assessed the frequency of foot deformities and surgery among patients recruited into the Inherited Neuropathies Consortium (INC). We also designed a survey addressed to orthopedic surgeons at INC centers to determine whether surgical approaches to orthopedic complications in CMT are variable.
Results:
Foot deformities were reported in 71% of CMT patients; 30% of the patients had surgery. Survey questions were answered by 16 surgeons working in different specialized centers. Most of the respondents were foot and ankle surgeons. There was marked variation in surgical management.
Discussion:
Our findings confirm that the approaches to orthopedic management of CMT are varied. We identify areas that require further research.
Muscle Nerve
57
: 255–259, 2018
Details
- Title: Subtitle
- Prevalence and orthopedic management of foot and ankle deformities in Charcot–Marie–Tooth disease
- Creators
- Matilde Laurá - University College London Institute of NeurologyDishan Singh - Royal National Orthopedic HospitalGita Ramdharry - St George's University of London/Kingston UniversityJasper Morrow - University College London Institute of NeurologyMariola Skorupinska - University College London Institute of NeurologyDavide Pareyson - IRCCS Foundation, Carlo Besta Neurological InstituteJoshua Burns - University of Sydney & Children's Hospital at WestmeadRichard A Lewis - Cedars Sinai Medical CenterSteven S Scherer - Hospital of the University of PennsylvaniaDavid N Herrmann - University of RochesterNicholas Cullen - Royal National Orthopedic HospitalChristopher Bradish - Great Ormond Street HospitalLuca Gaiani - ASLNicolò Martinelli - IRCCS GaleazziPaul Gibbons - University of Sydney & Children's Hospital at WestmeadGlenn Pfeffer - Cedars Sinai Medical CenterPhinit Phisitkul - University of Iowa Health CareKeith Wapner - University of PennsylvaniaJames Sanders - University of RochesterSam Flemister - University of RochesterMichael E Shy - University of Iowa health Care, Iowa CityMary M Reilly - University College London Institute of Neurology
- Resource Type
- Journal article
- Publication Details
- Muscle & nerve, Vol.57(2), pp.255-259
- DOI
- 10.1002/mus.25724
- PMID
- 28632967
- PMCID
- PMC5811923
- NLM abbreviation
- Muscle Nerve
- ISSN
- 0148-639X
- eISSN
- 1097-4598
- Publisher
- John Wiley and Sons Inc; Hoboken
- Grant note
- G0601943 / Medical Research Council National Institute for Health Research University College London Hospitals Biomedical Research Centre University College London U54NS065712 / National Institutes of Neurological Diseases and Stroke and Office of Rare Diseases National Institute for Health Research Biomedical Research Centre at Great Ormond Street Hospital for Children NHS Foundation Trust U54NS065712 / The Inherited Neuropathy Consortium
- Alternative title
- Management of CMT Foot Deformities
- Language
- English
- Date published
- 02/2018
- Academic Unit
- Neurology; Molecular Physiology and Biophysics; Stead Family Department of Pediatrics; Iowa Neuroscience Institute
- Record Identifier
- 9984070652602771
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