Journal article
Prevalence of Depressive Symptoms Early in the Course of Schizophrenia
American Journal of Psychiatry, Vol.156(2), pp.315-316
02/01/1999
DOI: 10.1176/ajp.156.2.315
PMID: 9989572
Abstract
OBJECTIVE: The rate of depressive symptoms early in the course of schizophrenia was determined. METHOD: Seventy subjects with recent-onset schizophrenia were followed for 5 years by using semistructured interview instruments. The initial assessment included ratings of each criterion A symptom of a DSM-III-R major depressive episode. The rates of symptoms experienced with at least moderate severity were calculated, and an algorithm based on DSM identified subjects meeting the criteria for a major depressive episode. RESULTS: Four symptoms were present to at least a moderate degree in a majority of subjects, while no symptom was present in fewer than 12% of subjects. More than one-third of the subjects met the algorithmic criteria for a major depressive episode at the time of intake. CONCLUSIONS: Depressive symptoms are common early in the course of schizophrenia. This finding is consistent with other recent data and has potential implications for current diagnostic and treatment practices.
Details
- Title: Subtitle
- Prevalence of Depressive Symptoms Early in the Course of Schizophrenia
- Creators
- Thomas H WassinkMichael FlaumPeg NopoulosNancy C Andreasen
- Resource Type
- Journal article
- Publication Details
- American Journal of Psychiatry, Vol.156(2), pp.315-316
- Publisher
- American Psychiatric Publishing
- DOI
- 10.1176/ajp.156.2.315
- PMID
- 9989572
- ISSN
- 0002-953X
- eISSN
- 1535-7228
- Language
- English
- Date published
- 02/01/1999
- Academic Unit
- Neurology; Psychiatry; Stead Family Department of Pediatrics; Iowa Neuroscience Institute
- Record Identifier
- 9984004189002771
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