Journal article
Prevalence of neonicotinoid insecticides in paired private-well tap water and human urine samples in a region of intense agriculture overlying vulnerable aquifers in eastern Iowa
Chemosphere (Oxford), Vol.319, 137904
04/2023
DOI: 10.1016/j.chemosphere.2023.137904
PMCID: PMC9957962
PMID: 36709846
Abstract
A pilot study among farming households in eastern Iowa was conducted to assess human exposure to neonicotinoids (NEOs). The study was in a region with intense crop and livestock production and where groundwater is vulnerable to surface-applied contaminants. In addition to paired outdoor (hydrant) water and indoor (tap) water samples from private wells, urine samples were collected from 47 adult male pesticide applicators along with the completions of dietary and occupational surveys. Estimated Daily Intake (EDI) were then calculated to examine exposures for different aged family members. NEOs were detected in 53% of outdoor and 55% of indoor samples, with two or more NEOs in 13% of samples. Clothianidin was the most frequently detected NEO in water samples. Human exposure was ubiquitous in urine samples. A median of 10 different NEOs and/or metabolites were detected in urine, with clothianidin, nitenpyram, thiamethoxam, 6-chloronicotinic acid, and thiacloprid amide detected in every urine samples analyzed. Dinotefuran, imidaclothiz, acetamiprid-N-desmethyl, and N-desmethyl thiamethoxam were found in ≥70% of urine samples. Observed water intake for study participants and EDIs were below the chronic reference doses (CRfD) and acceptable daily intake (ADI) standards for all NEOs indicating minimal risk from ingestion of tap water. The study results indicate that while the consumption of private well tap water provides a human exposure pathway, the companion urine results provide evidence that diet and/or other exposure pathways (e.g., occupational, house dust) may contribute to exposure more than water contamination. Further biomonitoring research is needed to better understand the scale of human exposure from different sources.
Details
- Title: Subtitle
- Prevalence of neonicotinoid insecticides in paired private-well tap water and human urine samples in a region of intense agriculture overlying vulnerable aquifers in eastern Iowa
- Creators
- Darrin A. Thompson - University of IowaDana W. Kolpin - United States Geological SurveyMichelle L. Hladik - United States Geological SurveyHans-Joachim Lehmler - University of IowaShannon M. Meppelink - United States Geological SurveyMatthew C. Poch - University of IowaJohn D. Vargo - University of IowaVictor A. Soupene - University of IowaNafis Md Irfan - University of DhakaMorgan Robinson - New York UniversityKurunthachalam Kannan - New York UniversityLaura E. Beane FreemanJonathan N. Hofmann - National Cancer InstituteDavid M. Cwiertny - University of IowaR. William Field - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Chemosphere (Oxford), Vol.319, 137904
- DOI
- 10.1016/j.chemosphere.2023.137904
- PMID
- 36709846
- PMCID
- PMC9957962
- NLM abbreviation
- Chemosphere
- ISSN
- 0045-6535
- eISSN
- 1879-1298
- Grant note
- DOI: 10.13039/100000066, name: National Institute of Environmental Health Sciences; DOI: 10.13039/100000125, name: National Institute for Occupational Safety and Health
- Language
- English
- Electronic publication date
- 01/2023
- Date published
- 04/2023
- Academic Unit
- Center for Health Effects of Environmental Contamination; Civil and Environmental Engineering; Occupational and Environmental Health; Epidemiology; Iowa Neuroscience Institute; Injury Prevention Research Center; Public Policy Center (Archive); Chemistry; Chemical and Biochemical Engineering
- Record Identifier
- 9984363547302771
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