Prevalence of non-cavitated lesions and progression, regression, and no change from age 9 to 23 years

Mahrukh Zafar; Steven M. Levy; John J. Warren; Xian Jin Xie; Justine Kolker; Chandler Pendleton

doi:10.1111/jphd.12538

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Prevalence of non-cavitated lesions and progression, regression, and no change from age 9 to 23 years

Journal article

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Prevalence of non-cavitated lesions and progression, regression, and no change from age 9 to 23 years

Mahrukh Zafar, Steven M. Levy, John J. Warren, Xian Jin Xie, Justine Kolker and Chandler Pendleton

Journal of public health dentistry, Vol.82(3), pp.313-320

06/01/2022

DOI: 10.1111/jphd.12538

PMCID: PMC9544189

PMID: 35781658

Appears in UI Libraries Support Open Access

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Abstract

Objectives Some non-cavitated caries lesions (D-1), the initial stage of caries, progress to cavitation. This article reports participant-level and surface-level D-1 prevalence and changes in status of D-1 lesions through different periods from age 9 to 23. Methods The Iowa Fluoride Study (IFS) participants were followed longitudinally; all permanent tooth surfaces were examined clinically for caries at ages 9, 13, 17, and 23 using standardized criteria for sound (S), questionable (D-0), non-cavitated (D-1), cavitated (D2+), filled (F), or missing due to decay (M). D-1 lesions at the beginning of each interval were reassessed at each follow-up age to determine transitions (to the 5 categories or no transition). Results The sample had relatively high socioeconomic status (SES), with about 52%-55% high SES, 32-35% middle SES, and 12-13% low SES. Person-level prevalences of D-1 lesions were 23%, 38%, 60%, and 45% at ages 9, 13, 17, and 23, respectively. Surface-level prevalences were less than 1% at ages 9 and 13, 3% at 17, and 2% at 23. Thirteen percent of D(1)s at age 9 progressed at 13, 18% progressed from 13 to 17, and 11% progressed from 17 to 23. The percentages regressing (to sound or D-0) were 72%, 54%, and 72%, respectively. Conclusion Non-cavitated lesions were more prevalent at age 17 than at ages 9, 13, and 23. The high rates of regression compared to progression or no change suggest that many non-cavitated lesions do not progress to cavitated lesions and could be reversed; therefore, surgical intervention should not be the treatment of choice for incipient lesions.

Dentistry, Oral Surgery & Medicine

Life Sciences & Biomedicine

Public, Environmental & Occupational Health

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Details

Title: Subtitle: Prevalence of non-cavitated lesions and progression, regression, and no change from age 9 to 23 years
Creators: Mahrukh Zafar - University of Iowa
Steven M. Levy - University of Iowa
John J. Warren - University of Iowa
Xian Jin Xie - University of Iowa
Justine Kolker - University of Iowa
Chandler Pendleton - University of Iowa
Resource Type: Journal article
Publication Details: Journal of public health dentistry, Vol.82(3), pp.313-320
DOI: 10.1111/jphd.12538
PMID: 35781658
PMCID: PMC9544189
NLM abbreviation: J Public Health Dent
ISSN: 0022-4006
eISSN: 1752-7325
Publisher: Wiley
Number of pages: 8
Grant note: M01-RR00059; R01-DE09551; R01-DE12101; R03-DE023784; R56-DE012101; UL1-RR024979; UL1-TR000442; UL1-TR001013 / U.S. National Institute of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA Delta Dental of Iowa Foundation Roy J. Carver Charitable Trust
Language: English
Date published: 06/01/2022
Academic Unit: Preventive and Community Dentistry; Epidemiology; Biostatistics; Operative Dentistry; Dental Research
Record Identifier: 9984323339802771

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