Journal article
Primary Non-Hodgkin's Lymphoma of the Gallbladder:. Population-based Analysis
Anticancer research, Vol.37(5), pp.2581-2586
05/01/2017
DOI: 10.21873/anticanres.11602
PMID: 28476830
Abstract
Background/Aim: Primary Non-Hodgkin's lymphoma of the gallbladder (PNHL-GB) is extremely rare and data on clinical characteristics, optimal management and outcomes of these patients are limited to anecdotal reporting. We, therefore, sought to examine these patients using a population-based database. Materials and Methods: Surveillance, epidemiology, and end results (SEER) database was queried between 1973 and 2013. Results: One hundred and six cases with PNHL-GB were identified (mean age=70.5 +/- 15 years, whites 92%, male: female 1.03:1). The majority of patients had loco-regional disease (61%) and DLBCL histology (33%). Ninenty cases (85%) had undergone surgical resection, 6 (5.6%) received radiotherapy. Median overall survival (OS) of the entire cohort was 41 months with a 5-year survival rate of 40%. Patients receiving adjuvant RT had superior OS compared to surgery alone (140 +/- 27 vs. 86 +/- 16 months, respectively) and patients with DLBCL demonstrated lower survival compared to other histologies (13 vs. 53 months, respectively, p=0.034). Conclusion: Our study presents the largest dataset of PNHL-GB describing clinical features and outcomes of these patients in addition to summarizing the literature.
Details
- Title: Subtitle
- Primary Non-Hodgkin's Lymphoma of the Gallbladder:. Population-based Analysis
- Creators
- Adil Ayub - Mount Sinai Health SystemSadiq Rehmani - Mount Sinai Health SystemAdnan M. Al-Ayoubi - Mt Sinai Hlth Syst, Icahn Sch Med, Dept Surg, New York, NY USAErik Lewis - Mt Sinai Hlth Syst, Icahn Sch Med, Dept Surg, New York, NY USANorberto Santana-Rodriguez - Mount Sinai Health SystemWissam Raad - Mount Sinai Health SystemFaiz Bhora - Mount Sinai Health SystemGrace Kim - Mount Sinai Health System
- Resource Type
- Journal article
- Publication Details
- Anticancer research, Vol.37(5), pp.2581-2586
- Publisher
- Int Inst Anticancer Research
- DOI
- 10.21873/anticanres.11602
- PMID
- 28476830
- ISSN
- 0250-7005
- eISSN
- 1791-7530
- Number of pages
- 6
- Language
- English
- Date published
- 05/01/2017
- Academic Unit
- Cardiothoracic Surgery
- Record Identifier
- 9984701823702771
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