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Primary Noncutaneous Malignant Melanoma of the Breast
Journal article   Peer reviewed

Primary Noncutaneous Malignant Melanoma of the Breast

Mohammad Rassouli and Ioannis A. Voutsadakis
The breast journal, Vol.22(6), pp.688-691
11/2016
DOI: 10.1111/tbj.12661
PMID: 27488963

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Abstract

Primary noncutaneous breast melanoma without an apparent skin primary lesion is uncommon. Its pathogenesis is debated with some authors believing that it is a metastatic disease from an undiscovered primary or a primary that has since completely regressed but it may be a true primary tumor arising from ectopic melanocytes. We present a case of a V600E BRAF mutation‐positive primary noncutaneous breast melanoma diagnosed at an early stage in a screening mammogram as a solitary breast lesion without nodal involvement. Considerations of treatment of this rare disease are discussed.
BRAF breast malignant melanoma noncutaneous parenchymal Primary

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