Journal article
Primary Squamous Cell Cancer of the Vulva: Radical versus Modified Radical Vulvar Surgery
Gynecologic Oncology, Vol.71(1), pp.116-121
10/1998
DOI: 10.1006/gyno.1998.5149
PMID: 9784331
Abstract
Objective.To evaluate the results of surgical therapy and to specifically compare radical and modified radical vulvar surgery relative to survival, recurrence, metastasis, and complications. Methods.A retrospective review of 225 patients with primary squamous cell cancer of the vulva was performed. Clinical, pathologic, surgical, and follow-up data were collected from the patient records. All pathology slides were reviewed with a pathologist. Radical surgery included 134 patients treated by the Basset operation. Modified radical surgery accounted for 91 patients with vulvar excision alone (65) or with lymphadenectomy (26) via separate groin incisions. Results.The 5-year recurrence rate was 14%. The overall and disease-free survival rates at 5 years were 76.1 and 83.4%, respectively. There were no statistically significant differences between the two procedures regarding overall survival, disease-free survival, or the development of recurrence, even after adjusting for stage (P> 0.05). Patients undergoing radical vulvar surgery were more likely to develop surgical complications and sequelae than patients having modified radical surgery, even after adjusting for stage. Conclusions.Modified radical vulvar surgery is associated with decreased complications and 5-year overall and disease-free survival and recurrence rates similar to those of radical vulvar surgery.
Details
- Title: Subtitle
- Primary Squamous Cell Cancer of the Vulva: Radical versus Modified Radical Vulvar Surgery
- Creators
- Javier F Magrina - Department of Obstetrics and Gynecology, Mayo Clinic Scottsdale, Scottsdale, Arizona, 85259Jesus Gonzalez-Bosquet - Hospital vall D'Hebron, Barcelona, SpainAmy L Weaver - Section of Biostatistics, Mayo Clinic and Mayo Foundation, Rochester, MinnesotaThomas A Gaffey - Division of Anatomic Pathology, Mayo Clinic and Mayo Foundation, Rochester, MinnesotaMaurice J Webb - Section of Gynecologic Surgery, Mayo Clinic and Mayo Foundation, Rochester, MinnesotaKarl C Podratz - Section of Gynecologic Surgery, Mayo Clinic and Mayo Foundation, Rochester, MinnesotaJeffrey L Cornella - Department of Obstetrics and Gynecology, Mayo Clinic Scottsdale, Scottsdale, Arizona, 85259
- Resource Type
- Journal article
- Publication Details
- Gynecologic Oncology, Vol.71(1), pp.116-121
- Publisher
- Elsevier Inc
- DOI
- 10.1006/gyno.1998.5149
- PMID
- 9784331
- ISSN
- 0090-8258
- eISSN
- 1095-6859
- Language
- English
- Date published
- 10/1998
- Academic Unit
- Obstetrics and Gynecology
- Record Identifier
- 9983930993702771
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