Journal article
Primary human immunodeficiency virus infection during pregnancy detected by repeat testing
American journal of obstetrics and gynecology, Vol.197(2), pp.149.e1-149.e5
08/01/2007
DOI: 10.1016/j.ajog.2007.03.030
PMID: 17689629
Abstract
The purpose of this study was to describe characteristics of pregnant women with newly acquired human immunodeficiency virus (HIV) infection that was identified by repeat testing.
The Centers for Disease Control and Prevention–sponsored Mother-Infant Rapid Intervention at Delivery (MIRIAD) study, which was conducted in 6 US cities, encouraged repeat HIV testing during pregnancy to identify primary infections.
Fifty-four HIV-infected women were identified. Four primary HIV infections were recognized, with median estimated seroconversion at 22 weeks of gestation. All 4 women denied new sex partners, alcohol, and illegal drug use during pregnancy. Three of the 4 mother-infant pairs received antiretroviral medications. One infant was infected perinatally, with positive HIV DNA polymerase chain reaction at birth. Questionnaire data identified 2 additional women with HIV that was likely acquired during pregnancy (identified by rapid testing at labor and delivery), which suggests that 6 of 54 HIV-infected women (11%) in the MIRIAD study had primary infection during pregnancy.
Repeat HIV testing in pregnancy can identify opportunities for antiretroviral prophylaxis and should be used in areas of high HIV prevalence.
Details
- Title: Subtitle
- Primary human immunodeficiency virus infection during pregnancy detected by repeat testing
- Creators
- Steven Nesheim - Emory University School of MedicineDenise J. Jamieson - Centers for Disease Control and PreventionSusan P. Danner - National Center for HIV/AIDS Viral Hepatitis STD and TB PreventionRobert Maupin - Louisiana State UniversityMary Jo O’Sullivan - University of MiamiMardge H. Cohen - Cook County Department of Public HealthMayris P. Webber - Albert Einstein College of MedicineRenata Dennis - Emory University School of MedicineMarc Bulterys - National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention
- Resource Type
- Journal article
- Publication Details
- American journal of obstetrics and gynecology, Vol.197(2), pp.149.e1-149.e5
- Publisher
- Mosby, Inc
- DOI
- 10.1016/j.ajog.2007.03.030
- PMID
- 17689629
- ISSN
- 0002-9378
- eISSN
- 1097-6868
- Language
- English
- Date published
- 08/01/2007
- Academic Unit
- Obstetrics and Gynecology; VPMA - Administration
- Record Identifier
- 9984446557902771
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