Journal article
Probing the role of nonmuscle tropomyosin isoforms in intracellular granule movement by microinjection of monoclonal antibodies
The Journal of cell biology, Vol.109(3), pp.1141-1152
01/01/1989
DOI: 10.1083/jcb.109.3.1141
PMCID: PMC2115770
PMID: 2670955
Abstract
Chicken embryo fibroblast cells were microinjected with several different monoclonal antibodies that recognize certain nonmuscle isoforms of tropomyosin. Immediately after injection, cells were recorded with a time-lapse video imaging system; later analysis of the tapes revealed that particles in cells injected with one of these antibodies showed a dramatic decrease in instantaneous speed while moving, distance moved per saltation, and proportion of time spent in motion.
Details
- Title: Subtitle
- Probing the role of nonmuscle tropomyosin isoforms in intracellular granule movement by microinjection of monoclonal antibodies
- Creators
- T E Hegmann - University of IowaJenny LinJim Lin
- Resource Type
- Journal article
- Publication Details
- The Journal of cell biology, Vol.109(3), pp.1141-1152
- DOI
- 10.1083/jcb.109.3.1141
- PMID
- 2670955
- PMCID
- PMC2115770
- NLM abbreviation
- J Cell Biol
- ISSN
- 0021-9525
- eISSN
- 1540-8140
- Language
- English
- Date published
- 01/01/1989
- Academic Unit
- Physician Assistant Studies; Biology
- Record Identifier
- 9984295060002771
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