Journal article
Prognosis and Predictors of ACL Reconstructions using the MOON Cohort: A Model for Comparative Effectiveness Studies
Journal of orthopaedic research, Vol.31(1), pp.2-9
01/2013
DOI: 10.1002/jor.22201
PMCID: PMC3508257
PMID: 22912340
Abstract
Injury to the anterior cruciate ligament (ACL) threatens an active lifestyle and exposes the patient to risk of early osteoarthritis (OA). ACL reconstruction is typically chosen by individuals to allow a return to their previous work and sports activities. Primary ACL reconstruction (ACLR) has in general been effective at restoring functional stability, but patients’ modifiable predictors of both short- and long-term validated outcomes and OA are largely unknown.
The Multicenter Orthopaedic Outcomes Network (MOON) consortium was established in 2002 to enroll and longitudinally follow a population cohort of ACL reconstructed patients. The objective was to establish patient-specific predictive models of clinically important outcomes. Over the past 10 years, the overarching aims of this NIAMS-funded prospective multicenter cohort of ACL reconstructions has been three-fold: 1) to identify both short- and long-term prognosis and predictors of sports function, activity level, and general health through validated patient-reported outcomes, 2) to identify the symptoms and signs of OA, and 3) to quantify the incidence of ACL reconstruction graft and/or contralateral ACL failures and additional surgical procedures.
This manuscript summarizes the Kappa Delta Ann Doner Vaughan Award paper and presentation at the 2012 ORS/AAOS Annual Meeting.
Details
- Title: Subtitle
- Prognosis and Predictors of ACL Reconstructions using the MOON Cohort: A Model for Comparative Effectiveness Studies
- Creators
- Kurt P Spindler - Vanderbilt University Medical Center, Nashville, TNRichard D Parker - Cleveland Clinic Foundation, Cleveland, OHJack T Andrish - Cleveland Clinic Foundation, Cleveland, OHChristopher C Kaeding - The Ohio State University, Columbus, OHRick W Wright - Washington University at St. Louis, St. Louis, MORobert G Marx - Hospital for Special Surgery, New York, NYEric C McCarty - University of Colorado, Denver, COAnnunziato Amendola - University of Iowa, Iowa City, IAWarren R Dunn - Vanderbilt University Medical Center, Nashville, TNLaura J Huston - Vanderbilt University Medical Center, Nashville, TNFrank E Harrell - Vanderbilt University Medical Center, Nashville, TNMOON Group (Multicenter Orthopedic Outcomes Network)
- Contributors
- Brian R Wolf (Contributor) - University of Iowa, Orthopedics and Rehabilitation
- Resource Type
- Journal article
- Publication Details
- Journal of orthopaedic research, Vol.31(1), pp.2-9
- DOI
- 10.1002/jor.22201
- PMID
- 22912340
- PMCID
- PMC3508257
- ISSN
- 0736-0266
- eISSN
- 1554-527X
- Grant note
- K23 AR052392 || AR / National Institute of Arthritis and Musculoskeletal and Skin Diseases : NIAMS
- Language
- English
- Date published
- 01/2013
- Academic Unit
- Orthopedics and Rehabilitation; Physical Therapy and Rehabilitation Science
- Record Identifier
- 9984040562002771
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