Logo image
Progress in the Management of Pancreatic Neuroendocrine Tumors
Journal article   Open access   Peer reviewed

Progress in the Management of Pancreatic Neuroendocrine Tumors

Amy Chang, Scott K. Sherman, James R. Howe and Vaibhav Sahai
Annual review of medicine, Vol.73(1), pp.213-229
01/01/2022
DOI: 10.1146/annurev-med-042320-011248
PMID: 34669433
url
https://doi.org/10.1146/annurev-med-042320-011248View
Published (Version of record) Open Access

Abstract

Pancreatic neuroendocrine tumors (PNETs) are a heterogeneous and orphan group of neoplasms that vary in their histology, clinical features, prognosis, and management. The treatment of PNETs is highly dependent on the stage at presentation, tumor grade and differentiation, presence of symptoms from hormonal overproduction or from local growth, tumor burden, and rate of progression. The US Food and Drug Administration has recently approved many novel treatments, which have altered decision making and positively impacted the care and prognosis of these patients. In this review, we focus on the significant progress made in the management of PNETs over the past decade, as well as the active areas of research.
Life Sciences & Biomedicine Medicine, Research & Experimental Research & Experimental Medicine Science & Technology

Details

Metrics

Logo image