Journal article
Progressive Exercise Training Improves Cardiovascular Psychophysiological Outcomes in Young Adult Women with a History of Adverse Childhood Experiences
Journal of applied physiology (1985), Vol.134(3), pp.742-752
03/2023
DOI: 10.1152/japplphysiol.00524.2022
PMCID: PMC10027078
PMID: 36727632
Abstract
Adverse childhood experiences (ACEs) are early life psychosocial stressors that are associated with poorer mental health and increased cardiovascular disease (CVD) risk in a dose-dependent manner. We examined the feasibility of an 8-week combined aerobic and resistance exercise training program to improve systolic (SBP) and diastolic blood pressure (DBP), serum endothelin-1 (ET-1), resilience, hope agency, and hope pathways in young women with ACEs. Forty-two healthy women (21±3 y) with ≥4 (ACE+; n=28) or 0 ACEs (ACE-; n=14) completed this study. Women with ACEs were randomly assigned to an exercise (ACE+
; n=14) or non-exercise control (ACE+
;n=14) group, whereas all ACE- participants were assigned to a non-exercise control (n=14). Hope agency and DBP did not change in any group (p³0.43), but hope pathways improved only in ACE+
(mean±SE change; +1.6±0.74 au; p=0.032). ET-1 decreased in ACE+
only (-0.31±0.15 pg/ml, p=0.043). Although the interactions for resilience and SBP did not reach significance (p=0.05---0.06), forced post-hoc analyses indicated that resilience improved (+4.9±1.9 au, p = 0.012) and SBP tended to improve (-4.0±2.0 mmHg; p=0.053) in ACE+
only. There were significant associations between changes in hope pathways and SBP (ρ=-0.43, p=0.023) and ET-1 (ρ=-0.53, p=0.005), and between changes in SBP and ET-1 (ρ=0.49; p=0.012) in the ACE+ group. In summary, structured exercise training reduces serum ET-1 levels, improves positive psychological coping, and may improve SBP in young women with ACEs. The relationships among the changes in hope pathways, SBP, and ET-1 suggest a cardiovascular psychophysiological relationship in young women with ACEs.
Details
- Title: Subtitle
- Progressive Exercise Training Improves Cardiovascular Psychophysiological Outcomes in Young Adult Women with a History of Adverse Childhood Experiences
- Creators
- Emily M Rogers - University of IowaNile F Banks - University of IowaPatrick M Tomko - Kent State UniversityChristina M Sciarillo - Baylor College of MedicineSam R Emerson - Oklahoma State UniversityEmily B K Thomas - University of IowaAshlee Taylor - University of OklahomaT Kent Teague - Oklahoma State UniversityNathaniel D M Jenkins - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of applied physiology (1985), Vol.134(3), pp.742-752
- DOI
- 10.1152/japplphysiol.00524.2022
- PMID
- 36727632
- PMCID
- PMC10027078
- NLM abbreviation
- J Appl Physiol (1985)
- eISSN
- 1522-1601
- Grant note
- P20GM109097 / HHS | NIH | National Institute of General Medical Sciences (NIGMS)
- Language
- English
- Electronic publication date
- 02/02/2023
- Date published
- 03/2023
- Academic Unit
- Psychological and Brain Sciences; Center for Social Science Innovation; Injury Prevention Research Center; Health, Sport, and Human Physiology ; Internal Medicine
- Record Identifier
- 9984363652902771
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