Journal article
Projected benefits of active surveillance for vancomycin-resistant enterococci in intensive care units
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Vol.38(8), pp.1108-1115
04/15/2004
DOI: 10.1086/382886
PMID: 15095215
Abstract
Hospitals use many strategies to control nosocomial transmission of vancomycin-resistant enterococci (VRE). Strategies include "passive surveillance," with isolation of patients with known previous or current VRE colonization or infection, and "active surveillance," which uses admission cultures, with subsequent isolation of patients who are found to be colonized with VRE. We created a mathematical model of VRE transmission in an intensive care unit (ICU) using data from an existing active surveillance program; we used the model to generate the estimated benefits associated with active surveillance. Simulations predicted that active surveillance in a 10-bed ICU would result in a 39% reduction in the annual incidence of VRE colonization when compared with no surveillance. Initial isolation of all patients, with withdrawal of isolation if the results of surveillance cultures are negative, was predicted to result in a 65% reduction. Passive surveillance was minimally effective. Using the best available data, active surveillance is projected to be effective for reducing VRE transmission in ICU settings.
Details
- Title: Subtitle
- Projected benefits of active surveillance for vancomycin-resistant enterococci in intensive care units
- Creators
- Eli N Perencevich - Veterans' Affairs Maryland Healthcare System, Baltimore, Maryland, USA. eperence@epi.umaryland.eduDavid N FismanMarc LipsitchAnthony D HarrisJ Glenn Morris JrDavid L Smith
- Resource Type
- Journal article
- Publication Details
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Vol.38(8), pp.1108-1115
- Publisher
- United States
- DOI
- 10.1086/382886
- PMID
- 15095215
- ISSN
- 1058-4838
- eISSN
- 1537-6591
- Grant note
- K23 AI01752-01A1 / NIAID NIH HHS
- Language
- English
- Date published
- 04/15/2004
- Academic Unit
- Epidemiology; Internal Medicine
- Record Identifier
- 9983779489802771
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