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Projecting Month of Birth for At-Risk Infants after Zika Virus Disease Outbreaks
Journal article   Open access   Peer reviewed

Projecting Month of Birth for At-Risk Infants after Zika Virus Disease Outbreaks

Jennita Reefhuis, Suzanne M. Gilboa, Michael A. Johansson, Diana Valencia, Regina M. Simeone, Susan L. Hills, Kara Polen, Denise J. Jamieson, Lyle R. Petersen and Margaret A. Honein
Emerging infectious diseases, Vol.22(5), pp.828-832
05/01/2016
DOI: 10.3201/eid2205.160290
PMCID: PMC4861542
PMID: 27088494
url
https://doi.org/10.3201/eid2205.160290View
Published (Version of record) Open Access

Abstract

The marked increase in infants born with microcephaly in Brazil after a 2015 outbreak of Zika virus disease suggests an association between maternal Zika virus infection and congenital microcephaly. To project the timing of delivery of infants born to mothers infected during early pregnancy in 1 city in Bahia State, Brazil, we incorporated data on reported Zika cases and microcephaly cases into a graphical schematic of weekly birth cohorts. We projected that these births would occur through February 2016. Applying similar projections to a hypothetical location at which Zika virus transmission started in November, we projected that full term infants at risk for Zika virus infection would be born during April September 2016. We also developed a modifiable spreadsheet tool that public health officials and researchers can use for their countries to plan for deliveries of infants to women who were infected with Zika virus during different pregnancy trimesters.
Immunology Infectious Diseases Life Sciences & Biomedicine Science & Technology

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