Journal article
Prolonged QT interval and risk of sudden death in South-East Asian men
The Lancet (British edition), Vol.338(8762), pp.280-281
08/03/1991
DOI: 10.1016/0140-6736(91)90419-P
PMID: 1677112
Abstract
Sudden death in sleep occurs in substantial numbers among young men in South-East Asia. The frequencies of electrocardiographic abnormalities were measured in groups with varying risks of such sudden death. The mean heart-rate-corrected QT interval (QTc) was significantly (p less than 0.05) greater among 123 Laotian refugees in Thailand at high risk (405 [95% confidence interval 397-413] ms) than in 77 Laotian refugees in the United States at lower risk (364 [359-369] ms) and 199 non-Asian US residents at negligible risk (358 [354-362] ms). Among refugees in Thailand, prolonged QTc interval was associated with poor thiamine status and a history of seizure-like episodes in sleep. Thiamine deficiency may be a cause of prolonged QT interval and sudden death in this region.
Details
- Title: Subtitle
- Prolonged QT interval and risk of sudden death in South-East Asian men
- Creators
- R G Munger - Department of Preventive Medicine and Environmental Health, University of Iowa College of Medicine, Iowa CityR J PrineasR S CrowS ChangbumrungV KeaneV WangsuphachartM P Jones
- Resource Type
- Journal article
- Publication Details
- The Lancet (British edition), Vol.338(8762), pp.280-281
- Publisher
- England
- DOI
- 10.1016/0140-6736(91)90419-P
- PMID
- 1677112
- ISSN
- 0140-6736
- eISSN
- 1474-547X
- Grant note
- 507RR-05548 / NCRR NIH HHS R01-HL-19877 / NHLBI NIH HHS
- Language
- English
- Date published
- 08/03/1991
- Academic Unit
- Statistics and Actuarial Science; Biostatistics; Public Policy Center (Archive)
- Record Identifier
- 9983985990202771
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