Prolonged use of continuous glucose monitors in children with type 1 diabetes on continuous subcutaneous insulin infusion or intensive multiple-daily injection therapy

Stuart Weinzimer; Dongyuan Xing; Michael Tansey; Rosanna Fiallo-Scharer; Nelly Mauras; Tim Wysocki; Roy Beck; William Tamborlane; Katrina Ruedy; Diabetes Research in Children Network Study Group

doi:10.1111/j.1399-5448.2008.00476.x

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Prolonged use of continuous glucose monitors in children with type 1 diabetes on continuous subcutaneous insulin infusion or intensive multiple-daily injection therapy

Journal article

Open access

Peer reviewed

Prolonged use of continuous glucose monitors in children with type 1 diabetes on continuous subcutaneous insulin infusion or intensive multiple-daily injection therapy

Stuart Weinzimer, Dongyuan Xing, Michael Tansey, Rosanna Fiallo-Scharer, Nelly Mauras, Tim Wysocki, Roy Beck, William Tamborlane, Katrina Ruedy and Diabetes Research in Children Network Study Group

Pediatric diabetes, Vol.10(2), pp.91-96

04/2009

DOI: 10.1111/j.1399-5448.2008.00476.x

PMID: 19175899

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Abstract

For continuous glucose sensors to improve the treatment of children with type 1 diabetes (T1D), they must be accurate, comfortable to wear, and easy to use. We conducted a pilot study of the FreeStyle Navigator Continuous Glucose Monitoring System (Abbott Diabetes Care) to examine the feasibility of daily use of a continuous glucose monitor (CGM) in an extended ambulatory setting. Following a 13-wk trial of daily Navigator use, 45 children with T1D [10.7 +/- 3.7 yr, range 4.6-17.6, 24 using insulin pumps; continuous subcutaneous insulin infusion (CSII) and 21 using glargine-based multiple daily injections (MDI)] used the Navigator for an additional 13 wk. Navigator use was initially slightly higher in the CSII users than in the MDI users but declined similarly in both groups by 22-26 wk. After 26 wk, 11 (46%) of 24 CSII users and 7 (33%) of 21 MDI users were using the CGM at least 5 d a week. No baseline demographic or clinical factors were predictive of the amount of sensor use at 26 wk. However, Navigator use during weeks 1-13 and scores on a CGM satisfaction survey at 13 wk were predictive of use in weeks 22-26. CGM was generally well-tolerated in children with T1D for more than 6 months, and early acceptance of CGM was predictive of extended use of the device. Although many subjects and parents found CGM valuable, the declining usage over time underscores the need to develop new technologies and strategies to increase acceptance, effectiveness, and long-term use of these devices in youth with T1D.

Blood Glucose - analysis

Humans

Child, Preschool

Insulin - administration & dosage

Male

Diabetes Mellitus, Type 1 - drug therapy

Pilot Projects

Hypoglycemic Agents - administration & dosage

Diabetes Mellitus, Type 1 - blood

Adolescent

Female

Insulin Infusion Systems

Surveys and Questionnaires

Patient Compliance

Blood Glucose Self-Monitoring - instrumentation

Child

Details

Title: Subtitle: Prolonged use of continuous glucose monitors in children with type 1 diabetes on continuous subcutaneous insulin infusion or intensive multiple-daily injection therapy
Creators: Stuart Weinzimer
Dongyuan Xing
Michael Tansey
Rosanna Fiallo-Scharer
Nelly Mauras
Tim Wysocki
Roy Beck
William Tamborlane
Katrina Ruedy
Diabetes Research in Children Network Study Group
Resource Type: Journal article
Publication Details: Pediatric diabetes, Vol.10(2), pp.91-96
DOI: 10.1111/j.1399-5448.2008.00476.x
PMID: 19175899
NLM abbreviation: Pediatr Diabetes
ISSN: 1399-543X
eISSN: 1399-5448
Grant note: HD041918-01 / NICHD NIH HHS HD041919-01 / NICHD NIH HHS M01 RR00069 / NCRR NIH HHS HD041915-01 / NICHD NIH HHS RR00059 / NCRR NIH HHS RR00070-41 / NCRR NIH HHS HD041908-01 / NICHD NIH HHS RR 06022 / NCRR NIH HHS HD041906-01 / NICHD NIH HHS HD041890 / NICHD NIH HHS
Language: English
Date published: 04/2009
Academic Unit: Endocrinology and Diabetes; Stead Family Department of Pediatrics; Fraternal Order of Eagles Diabetes Research Center
Record Identifier: 9984093348402771

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