Prophylactic Administration of Vasopressors Prior to Emergency Intubation in Critically Ill Patients: A Secondary Analysis of Two Multicenter Clinical Trials

Mikita Fuchita; Jack Pattee; Derek W. Russell; Brian E. Driver; Matthew E. Prekker; Christopher R. Barnes; Joseph M. Brewer; Kevin C. Doerschug; John P. Gaillard; Sheetal Gandotra; Shekhar Ghamande; Kevin W. Gibbs; Christopher G. Hughes; David R. Janz; Akram Khan; Steven H. Mitchell; David B. Page; Todd W. Rice; Wesley H. Self; Lane M. Smith; Susan B. Stempek; Stacy A. Trent; Derek J. Vonderhaar; Jason R. West; Micah R. Whitson; Kayla Williamson; Matthew W. Semler; Jonathan D. Casey; Adit A. Ginde

doi:10.1097/CCE.0000000000000946

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Prophylactic Administration of Vasopressors Prior to Emergency Intubation in Critically Ill Patients: A Secondary Analysis of Two Multicenter Clinical Trials

Journal article

Open access

Peer reviewed

Prophylactic Administration of Vasopressors Prior to Emergency Intubation in Critically Ill Patients: A Secondary Analysis of Two Multicenter Clinical Trials

Mikita Fuchita, Jack Pattee, Derek W. Russell, Brian E. Driver, Matthew E. Prekker, Christopher R. Barnes, Joseph M. Brewer, Kevin C. Doerschug, John P. Gaillard, Sheetal Gandotra, …

Critical care explorations, Vol.5(7), e0946

07/12/2023

DOI: 10.1097/CCE.0000000000000946

PMCID: PMC10344527

PMID: 37457916

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Abstract

Hypotension affects approximately 40% of critically ill patients undergoing emergency intubation and is associated with an increased risk of death. The objective of this study was to examine the association between prophylactic vasopressor administration and the incidence of peri-intubation hypotension and other clinical outcomes.

Critical Care

airway management

hypotension

intratracheal intubation

mechanical ventilation

Original Clinical Report

vasoconstrictor agents

Details

Title: Subtitle: Prophylactic Administration of Vasopressors Prior to Emergency Intubation in Critically Ill Patients: A Secondary Analysis of Two Multicenter Clinical Trials
Creators: Mikita Fuchita - University of Colorado Anschutz Medical Campus
Jack Pattee - Colorado School of Public Health
Derek W. Russell - University of Alabama at Birmingham
Brian E. Driver - Hennepin County Medical Center
Matthew E. Prekker - Hennepin County Medical Center
Christopher R. Barnes - University of Washington
Joseph M. Brewer - University of Mississippi Medical Center
Kevin C. Doerschug - University of Iowa
John P. Gaillard - Wake Forest University
Sheetal Gandotra - University of Alabama at Birmingham
Shekhar Ghamande - Baylor Scott & White Medical Center - Temple
Kevin W. Gibbs - Wake Forest University
Christopher G. Hughes - Vanderbilt University Medical Center
David R. Janz - University Medical Center New Orleans
Akram Khan - Oregon Health & Science University
Steven H. Mitchell - University of Washington
David B. Page - University of Alabama at Birmingham
Todd W. Rice - Vanderbilt University
Wesley H. Self - Vanderbilt University Medical Center
Lane M. Smith - University of Iowa
Susan B. Stempek - Lahey Hospital and Medical Center
Stacy A. Trent - Denver Health Medical Center
Derek J. Vonderhaar - Ochsner Health System
Jason R. West - New York City Health and Hospitals Corporation
Micah R. Whitson - University of Alabama at Birmingham
Kayla Williamson - Colorado School of Public Health
Matthew W. Semler - Vanderbilt University
Jonathan D. Casey - Vanderbilt University
Adit A. Ginde - University of Colorado Anschutz Medical Campus
Resource Type: Journal article
Publication Details: Critical care explorations, Vol.5(7), e0946
DOI: 10.1097/CCE.0000000000000946
PMID: 37457916
PMCID: PMC10344527
NLM abbreviation: Crit Care Explor
eISSN: 2639-8028
Publisher: Lippincott Williams & Wilkins
Language: English
Date published: 07/12/2023
Academic Unit: Pulmonary, Critical Care, and Occupational Medicine; Internal Medicine
Record Identifier: 9984443862302771

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