Journal article
Prospective change in daily walking over 2 years in older adults with or at risk of knee osteoarthritis: the MOST study
Osteoarthritis and cartilage, Vol.24(2), pp.246-253
02/2016
DOI: 10.1016/j.joca.2015.08.004
PMID: 26318659
Abstract
Radiographic disease and knee pain are thought to decrease physical activity in people with knee osteoarthritis (OA), but this has not been formally studied. We examined change in objectively measured daily walking over 2 years and evaluated the association of certain risk factors with reduced walking among adults with or at risk of knee OA.
Steps/day over 7 days were collected at baseline and 2 years later in subjects with or at risk of knee OA from the Multicenter Osteoarthritis Study using a StepWatch. We evaluated the presence of radiographic knee osteoarthritis (ROA), knee pain, worsening of ROA and pain over 2 years, obesity, depressive symptoms, living situation, catastrophizing, fatigue, widespread pain and comorbidities with 2-year change in daily walking using regression models adjusted for potential confounders.
1318 met inclusion criteria (age 66.9 ± 7.7, 59% women, BMI 30.6 ± 5.9) and walked 126 ± 1700 steps/day fewer steps at 2 years (95% CI [−218, −35]). People with depressive symptoms at baseline walked 455 fewer steps/day [−872, −68], and there was a trend for people with ROA worsening to walk 183 fewer steps/day [−377.5, 11.7]. No other factors met statistical significance for change in daily walking.
Adults with or at risk of knee OA experienced only minimal declines in daily walking over 2 years. Nonetheless, depressive symptoms and may be worsening ROA are associated with a decline in steps/day in adults with or at risk of knee OA.
Details
- Title: Subtitle
- Prospective change in daily walking over 2 years in older adults with or at risk of knee osteoarthritis: the MOST study
- Creators
- D.K White - Department of Physical Therapy, University of Delaware, Newark, DE, USAC Tudor-Locke - Department of Kinesiology, University of Massachusetts Amherst, Amherst MA, USAY Zhang - Boston UniversityJ Niu - Boston University School of Medicine, Boston, MA, USAD.T Felson - Boston University School of Medicine, Boston, MA, USAK.D Gross - Boston University School of Medicine, Boston, MA, USAM.C Nevitt - University of San Francisco, San Francisco, CA, USAC.E Lewis - University of Alabama, Birmingham, AL, USAJ Torner - University of Iowa, Iowa City, IA, USAT Neogi - Boston University School of Medicine, Boston, MA, USA
- Resource Type
- Journal article
- Publication Details
- Osteoarthritis and cartilage, Vol.24(2), pp.246-253
- DOI
- 10.1016/j.joca.2015.08.004
- PMID
- 26318659
- NLM abbreviation
- Osteoarthritis Cartilage
- ISSN
- 1063-4584
- eISSN
- 1522-9653
- Publisher
- Elsevier Ltd
- Grant note
- DOI: 10.13039/100000002, name: National Institutes of Health, award: AG18820, AG 18832, AG 18947, AG 19069, AR007598, AR47785; DOI: 10.13039/100000069, name: National Institute of Arthritis and Musculoskeletal and Skin Diseases, award: K23AR055127, R24HD0065688, R01AR062506; name: ACR/RRF Bridge Funding Award, the Boston Rehabilitation Outcomes Center (Boston ROC), award: R24HD0065688; name: Arthritis Foundation Arthritis Bridge Funding Award, Boston Claude D. Pepper Older Americans Independence Center, award: P30-AG031679; DOI: 10.13039/100009713, name: Foundation for Physical Therapy
- Language
- English
- Date published
- 02/2016
- Academic Unit
- Epidemiology; Surgery; Injury Prevention Research Center; Neurosurgery
- Record Identifier
- 9983995102602771
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