Journal article
Prospective epidemiologic evaluation of laboratory animal allergy among university employees
American Journal of Industrial Medicine, Vol.32(6), pp.665-669
1997
DOI: 10.1002/(SICI)1097-0274(199712)32:6<665::AID-AJIM13>3.0.CO;2-%23
Abstract
Objectives: Evaluation of incidence and risk factors for development of laboratory animal allergy (LAA) among new hires previously unexposed to lab animals. Methods: Baseline, 6-month and yearly follow-up, questionnaires, pulmonary functions, and methacholine challenges were collected from 98 never-before occupationally exposed and 90 control laboratory researchers. The two groups were followed between 6 and 36 months. Results: At baseline, there were no differences in atopy, pulmonary functions, or methacholine reactivity between the two groups. The incidence of work-related asthma was comparable in the two groups, approximately 2.5% at 6 months and 4.5% at 24 months. The rate of decline in FEV sub(1) was statistically significantly greater in the animal-exposed than nonanimal-exposed workers, and animal-exposed smokers' FEV sub(1) declined significantly more rapidly than any other groups. Conclusions: Despite the low incidence of laboratory-animal allergy and work-related asthma in this group, this study corroborates previously described interaction between smoking and animal exposure.
Details
- Title: Subtitle
- Prospective epidemiologic evaluation of laboratory animal allergy among university employees
- Creators
- Laurence J. Fuortes - University of IowaLeAnn WeihPaul PomrehnPeter S. Thorne - University of Iowa
- Resource Type
- Journal article
- Publication Details
- American Journal of Industrial Medicine, Vol.32(6), pp.665-669
- DOI
- 10.1002/(SICI)1097-0274(199712)32:6<665::AID-AJIM13>3.0.CO;2-%23
- ISSN
- 0271-3586
- eISSN
- 1097-0274
- Language
- English
- Date published
- 1997
- Academic Unit
- Internal Medicine; Occupational and Environmental Health; Civil and Environmental Engineering; Epidemiology
- Record Identifier
- 9983557691602771
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