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Prospective nerve conduction studies in cisplatin therapy
Journal article   Peer reviewed

Prospective nerve conduction studies in cisplatin therapy

Jack E Riggs, Mohammed Ashraf, Robert D Snyder and Ludwig Gutmann
Annals of neurology, Vol.23(1), pp.92-94
01/1988
DOI: 10.1002/ana.410230116
PMID: 3345071

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Abstract

We studied nerve conduction prospectively in 38 women receiving cisplatin for gynecological malignancies. Decreased sensory nerve action potential amplitudes and prolonged sensory latencies were the only significant changes identified. This prospective electrophysiological study validates the clinical observation of frequent sensory symptoms and occasional sensory neuropathies associated with cisplatin therapy.

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