Psychiatric and Medical Profiles of Autistic Adults in the SPARK Cohort

Eric Fombonne; LeeAnne Green Snyder; Amy Daniels; Pamela Feliciano; Wendy Chung; SPARK Consortium

doi:10.1007/s10803-020-04414-6

Back

Psychiatric and Medical Profiles of Autistic Adults in the SPARK Cohort

Journal article

Peer reviewed

Psychiatric and Medical Profiles of Autistic Adults in the SPARK Cohort

Eric Fombonne, LeeAnne Green Snyder, Amy Daniels, Pamela Feliciano, Wendy Chung and SPARK Consortium

Journal of autism and developmental disorders, Vol.50(10), pp.3679-3698

10/2020

DOI: 10.1007/s10803-020-04414-6

PMID: 32096123

View Online

Abstract

This study examined lifetime medical and psychiatric morbidity reported by caregivers of 2917 autistic adults participating in the US research cohort SPARK. Participants were 78.4% male, 47.3% had intellectual disability, and 32.1% had persistent language impairments. Childhood language disorders (59.7%), speech/articulation problems (32.8%), sleep (39.4%) and eating problems (29.4%), motor delays (22.8%) and history of seizure (15.5%) were the most frequently reported clinical features. Over two thirds (67.2%) had been diagnosed with at least one psychiatric disorder (anxiety disorders: 41.1%; ADHD: 38.7%). Compared to verbally fluent participants, those with language impairments had lower frequencies of almost all psychiatric disorders. Female sex and older age were associated with higher medical and psychiatric morbidity.

United States - epidemiology

Mental Disorders - epidemiology

Age Factors

Humans

Male

Autistic Disorder - epidemiology

Autistic Disorder - psychology

Mental Disorders - psychology

Young Adult

Anxiety Disorders - complications

Intellectual Disability - diagnosis

Adolescent

Sex Factors

Adult

Female

Intellectual Disability - psychology

Surveys and Questionnaires

Autistic Disorder - diagnosis

Mental Disorders - diagnosis

Cohort Studies

Intellectual Disability - epidemiology

Details

Title: Subtitle: Psychiatric and Medical Profiles of Autistic Adults in the SPARK Cohort
Creators: Eric Fombonne - Departments of Psychiatry, Pediatrics & Behavioral Neuroscience, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA. fombonne@ohsu.edu
LeeAnne Green Snyder - The Simons Foundation, New York, NY, USA
Amy Daniels - The Simons Foundation, New York, NY, USA
Pamela Feliciano - The Simons Foundation, New York, NY, USA
Wendy Chung - Department of Pediatrics, Columbia University Medical Center, New York, NY, USA
SPARK Consortium
Contributors: Jacob J Michaelson (Contributor) - University of Iowa, Roy J. Carver Department of Biomedical Engineering
Resource Type: Journal article
Publication Details: Journal of autism and developmental disorders, Vol.50(10), pp.3679-3698
Publisher: United States
DOI: 10.1007/s10803-020-04414-6
PMID: 32096123
ISSN: 0162-3257
eISSN: 1573-3432
Grant note: 383303 / Simons Foundation
Language: English
Date published: 10/2020
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Communication Sciences and Disorders; Psychiatry; Iowa Neuroscience Institute
Record Identifier: 9984070441702771

Metrics

40 Record Views

39 Times Cited - Web of Science

See more details