Journal article
Psychological treatment of perinatal depression: a meta-analysis
Psychological medicine, Vol.53(6), pp.2596-2608
04/2023
DOI: 10.1017/S0033291721004529
PMCID: PMC10123831
PMID: 37310303
Abstract
Background. Depression during pregnancy and after the birth of a child is highly prevalent and an important public health problem. Psychological interventions are the first-line treatment and, although a considerable number of randomized trials have been conducted, no recent comprehensive meta-analysis has evaluated treatment effects.
Methods. We used an existing database of randomized controlled trials of psychotherapies for adult depression and included studies aimed at perinatal depression. Random effects models were used in all analyses. We examined the effects of the interventions in the short and long term, and also examined secondary outcomes.
Results. Forty-three studies with 49 comparisons and 6270 participants between an intervention and control group were included. The overall effect size was g= 0.67 [95% confidence interval (CI) 0.45 similar to 0.89; numbers needed-to-be-treated = 4.39] with high heterogeneity (I-2 = 80%; 95% CI 75 similar to 85). This effect size remained largely unchanged and significant in a series of sensitivity analyses, although some publication bias was found. The effects remained significant at 6-12 months follow-up. Significant effects were also found for social support, anxiety, functional limitations, parental stress and marital stress, although the number of studies for each outcome was low. All results should be considered with caution because of the high levels of heterogeneity in most analyses.
Conclusions. Psychological interventions are probably effective in the treatment of perinatal depression, with effects that last at least up to 6-12 months and probably also have effects on social support, anxiety, functional impairment, parental stress, and marital stress.
Details
- Title: Subtitle
- Psychological treatment of perinatal depression: a meta-analysis
- Creators
- Pim Cuijpers - University of AmsterdamPamela Franco - Pontificia Univ Catolica Chile, Dept Psychol, Santiago, ChileMarketa Ciharova - University of AmsterdamClara Miguel - University of AmsterdamLisa Segre - University of IowaSoledad Quero - Univ Jaume 1, Dept Basic Clin Psychol & Psychobiol, Castellon de La Plana, SpainEirini Karyotaki - University of Amsterdam
- Resource Type
- Journal article
- Publication Details
- Psychological medicine, Vol.53(6), pp.2596-2608
- DOI
- 10.1017/S0033291721004529
- PMID
- 37310303
- PMCID
- PMC10123831
- NLM abbreviation
- Psychol Med
- ISSN
- 0033-2917
- eISSN
- 1469-8978
- Publisher
- Cambridge Univ Press
- Number of pages
- 13
- Grant note
- NACIONAL/2019-21190745 / Chilean National Agency for Research and Development (ANID) / Scholarship Program / DOCTORADO ISC III CB06 03/0052 / CIBEROBN, an initiative of the ISCIII
- Language
- English
- Electronic publication date
- 11/16/2021
- Date published
- 04/2023
- Academic Unit
- Nursing
- Record Identifier
- 9984370758602771
Metrics
12 Record Views