Journal article
Psychometrics evaluation of Charcot-Marie-Tooth Neuropathy Score (CMTNSv2) second version, using Rasch analysis
Journal of the peripheral nervous system, Vol.19(3), pp.192-196
09/2014
DOI: 10.1111/jns.12084
PMCID: PMC4303498
PMID: 25400013
Abstract
Charcot-Marie-Tooth Neuropathy Score second version (CMTNSv2) is a validated clinical outcome measure developed for use in clinical trials to monitor disease impairment and progression in affected CMT patients. Currently, all items of CMTNSv2 have identical contribution to the total score. We used Rasch analysis to further explore psychometric properties of CMTNSv2, and in particular, category response functioning and their weight on the overall disease progression. Weighted category responses represent a more accurate estimate of actual values measuring disease severity and therefore could potentially be used in improving the current version.
Details
- Title: Subtitle
- Psychometrics evaluation of Charcot-Marie-Tooth Neuropathy Score (CMTNSv2) second version, using Rasch analysis
- Creators
- Reza Sadjadi - Department of Neurology, University of Virginia, Charlottesville, VA, USAMary M Reilly - MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, UKMichael E Shy - Department of Neurology, College of Medicine, University of Iowa, Iowa City, IA USADavide Pareyson - Clinic of Central and Peripheral Degenerative Neuropathies Unit, Department of Clinical Neurosciences, IRCCS Foundation, C. Besta Neurological Institute, Milan, ItalyMatilde Laura - MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, UKSinead Murphy - Department of Neurology, Adelaide & Meath Hospitals incorporating the National Children’s Hospital, Tallaght, Dublin, and Trinity College Dublin, IrelandShawna M.E Feely - Department of Neurology, College of Medicine, University of Iowa, Iowa City, IA USATiffany Grider - Department of Neurology, College of Medicine, University of Iowa, Iowa City, IA USAChelsea Bacon - Department of Neurology, College of Medicine, University of Iowa, Iowa City, IA USAGiuseppe Piscosquito - Clinic of Central and Peripheral Degenerative Neuropathies Unit, Department of Clinical Neurosciences, IRCCS Foundation, C. Besta Neurological Institute, Milan, ItalyDaniela Calabrese - Clinic of Central and Peripheral Degenerative Neuropathies Unit, Department of Clinical Neurosciences, IRCCS Foundation, C. Besta Neurological Institute, Milan, ItalyTed M Burns - Department of Neurology, University of Virginia, Charlottesville, VA, USA
- Resource Type
- Journal article
- Publication Details
- Journal of the peripheral nervous system, Vol.19(3), pp.192-196
- DOI
- 10.1111/jns.12084
- PMID
- 25400013
- PMCID
- PMC4303498
- NLM abbreviation
- J Peripher Nerv Syst
- ISSN
- 1085-9489
- eISSN
- 1529-8027
- Grant note
- name: National Institutes of Health and Office of Rare Diseases, award: U54NS065712; DOI: 10.13039/100005202, name: Muscular Dystrophy Association; DOI: 10.13039/100002721, name: Charcot-Marie-Tooth Association
- Language
- English
- Date published
- 09/2014
- Academic Unit
- Neurology; Molecular Physiology and Biophysics; Psychiatry; Stead Family Department of Pediatrics; Iowa Neuroscience Institute
- Record Identifier
- 9984013919202771
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