Psychoneuroimmunology and cancer: A decade of discovery, paradigm shifts, and methodological innovations

Paige Green McDonald; Mary O’Connell; Susan K Lutgendorf

doi:10.1016/j.bbi.2013.01.003

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Psychoneuroimmunology and cancer: A decade of discovery, paradigm shifts, and methodological innovations

Journal article

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Psychoneuroimmunology and cancer: A decade of discovery, paradigm shifts, and methodological innovations

Paige Green McDonald, Mary O’Connell and Susan K Lutgendorf

Brain, behavior, and immunity, Vol.30, pp.S1-S9

03/15/2013

DOI: 10.1016/j.bbi.2013.01.003

PMCID: PMC3907949

PMID: 23333846

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Abstract

► This article introduces the National Cancer Institute sponsored supplement Advances in Cancer and Brain, Behavior, and Immunity and highlights the last decade of research in psychoneuroimmunology and cancer. This article introduces the supplement Advances in Cancer and Brain, Behavior, and Immunity and outlines important discoveries, paradigm shifts, and methodological innovations that have emerged in the past decade to advance mechanistic and translational understanding of biobehavioral influences on tumor biology, cancer treatment-related sequelae, and cancer outcomes. We offer a heuristic framework for research on biobehavioral pathways in cancer. The shifting survivorship landscape is highlighted, and we propose that the changing demographics suggest prudent adoption of a life course perspective of cancer and cancer survivorship. We note opportunities for psychoneuroimmunology (PNI) research to ameliorate the long-term, unintended consequences of aggressive curative intent and call attention to the critical role of reciprocal translational pathways between animal and human studies. Lastly, we briefly summarize the articles included in this compilation and offer our perspectives on future research directions.

Tumor biology

Psycho-oncology

Biobehavioral

Cancer treatment

Cancer outcomes

Details

Title: Subtitle: Psychoneuroimmunology and cancer: A decade of discovery, paradigm shifts, and methodological innovations
Creators: Paige Green McDonald - Basic Biobehavioral and Psychological Sciences Branch, Behavioral Research Program (BRP), Division of Cancer Control and Population Sciences (DCCPS), National Cancer Institute (NCI), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), United States
Mary O’Connell - BRP, DCCPS, NCI, NIH, DHHS, United States
Susan K Lutgendorf - Department of Psychology, University of Iowa, United States
Resource Type: Journal article
Publication Details: Brain, behavior, and immunity, Vol.30, pp.S1-S9
DOI: 10.1016/j.bbi.2013.01.003
PMID: 23333846
PMCID: PMC3907949
NLM abbreviation: Brain Behav Immun
ISSN: 0889-1591
eISSN: 1090-2139
Publisher: Elsevier Inc
Language: English
Date published: 03/15/2013
Academic Unit: Psychological and Brain Sciences; Iowa Neuroscience Institute; Obstetrics and Gynecology; Urology
Record Identifier: 9984002353702771

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