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Psychotropic medications and HIV
Journal article   Open access   Peer reviewed

Psychotropic medications and HIV

Alex Thompson, Benjamin Silverman, Liz Dzeng and Glenn Treisman
Clinical infectious diseases, Vol.42(9), pp.1305-1310
05/01/2006
DOI: 10.1086/501454
PMID: 16586391
url
https://doi.org/10.1086/501454View
Published (Version of record) Open Access

Abstract

Patients with human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome have high rates of psychiatric illness. The effective management of these psychiatric conditions can improve a patient's quality of life and may improve antiretroviral adherence. Care providers for patients with HIV infection frequently encounter clinical situations in which psychotropic medications are needed or are being used. Those clinical situations require familiarity with the broad category of medications termed "psychotropic." That familiarity should include a basic understanding of indications, adverse effects, and drug interactions. In particular, it is very important to recognize the many potential interactions based on cytochrome P450 metabolism, which is common to many psychotropics, the protease inhibitors, and the nonnucleoside reverse-transcriptase inhibitors. In a brief review of the use of psychotropic medications in patients with HIV infection, we discuss indications, adverse effects, and drug interactions for commonly used antidepressants, mood stabilizers, anxiolytics, antipsychotics, psychostimulants, and drugs of abuse.
 Anti-HIV Agents - adverse effects Anti-HIV Agents - therapeutic use Drug Interactions HIV Infections - complications HIV Infections - drug therapy Humans Mental Disorders - complications Mental Disorders - drug therapy Psychotropic Drugs - adverse effects Psychotropic Drugs - therapeutic use

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