Journal article
Pulmonary arteriovenous malformations: diagnostic and treatment characteristics
Jornal brasileiro de pneumologia, Vol.45(4), p.e20180137
2019
DOI: 10.1590/1806-3713/e20180137
PMCID: PMC6733713
PMID: 31241656
Abstract
Objective: To present a case series of pulmonary arteriovenous malformations (PAVMs), describing the main clinical findings, the number/location of pulmonary vascular abnormalities, the clinical complications, and the treatment administered. Methods: This was a retrospective observational study evaluating patients with PAVM divided into two groups: hereditary hemorrhagic telangiectasia (HHT); and idiopathic PAVM (iPAVM). Results: A total of 41 patients were selected for inclusion, but only 33 had PAVMs. After clinical evaluation, 27 and 6 were diagnosed with HHT and iPAVM, respectively. In the HHT group, the mean age was 49.6 years and 88.9% were female. In that group, 4 patients had an SpO(2) of < 90% and the most common clinical finding was epistaxis. In the iPAVM group, the mean age was 48.1 years and 83.3% were female. In that group, 3 patients had an SpO(2) of < 90%. Computed tomographic pulmonary angiography showed that most of the PAVMs were in the lower lobes: 56.4% in the HHT group and 85.7% in the iPAVM group. Embolization was performed in 23 patients (in both groups). At this writing, 10 patients are scheduled to undergo the procedure. One of the patients who underwent embolization was subsequently referred for pulmonary resection. Conclusions: In both of the PAVM groups, there was a predominance of women and of fistulas located in the lower lobes. Few of the patients had respiratory symptoms, and most had an SpO(2) > 90%. The treatment chosen for all patients was percutaneous transcatheter embolization.
Details
- Title: Subtitle
- Pulmonary arteriovenous malformations: diagnostic and treatment characteristics
- Creators
- William Salibe-Filho - Universidade de São PauloBruna Mamprim Piloto - Universidade de São PauloEllen Pierre de Oliveira - Universidade de São PauloMarcela Araujo Castro - Universidade de São PauloBreno Boueri Affonso - Universidade de São PauloJoaquim Mauricio da Motta-Leal-Filho - Universidade de São PauloEdgar Bortolini - Universidade de São PauloMario Terra-Filho - Universidade de São Paulo
- Resource Type
- Journal article
- Publication Details
- Jornal brasileiro de pneumologia, Vol.45(4), p.e20180137
- DOI
- 10.1590/1806-3713/e20180137
- PMID
- 31241656
- PMCID
- PMC6733713
- NLM abbreviation
- J Bras Pneumol
- ISSN
- 1806-3713
- eISSN
- 1806-3756
- Publisher
- Soc Brasileira Pneumologia Tisiologia
- Number of pages
- 7
- Language
- English
- Date published
- 2019
- Academic Unit
- Radiology
- Record Identifier
- 9985180933602771
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