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Pulmonary perfusion MRI using interleaved variable density sampling and HighlY constrained cartesian reconstruction (HYCR)
Journal article   Open access   Peer reviewed

Pulmonary perfusion MRI using interleaved variable density sampling and HighlY constrained cartesian reconstruction (HYCR)

Kang Wang, Mark L. Schiebler, Christopher J. Francois, A. Munoz Del Rio, Ma. Daniela Cornejo, Laura C. Bell, Frank R. Korosec, Jean H. Brittain, James H. Holmes and Scott K. Nagle
Journal of magnetic resonance imaging, Vol.38(3), pp.751-756
09/2013
DOI: 10.1002/jmri.24018
PMCID: PMC3638084
PMID: 23349079
url
https://doi.org/10.1002/jmri.24018View
Published (Version of record) Open Access

Abstract

Purpose: To demonstrate the feasibility of performing single breathhold, noncardiac gated, ultrafast, high spatial‐temporal resolution whole chest MR pulmonary perfusion imaging in humans. Materials and Methods: Eight subjects (five male, three female) were scanned with the proposed method on a 3 Tesla clinical scanner using a 32‐channel phased‐array coil. Seven (88%) were healthy volunteers, and one was a patient volunteer with sarcoidosis. The peak lung enhancement phase for each subject was scored for gravitational effect, peak parenchymal enhancement and severity of artifacts by three cardiothoracic radiologists independently. Results: All studies were successfully performed by MR technologists without any additional training. Mean parenchymal signal was very good, measuring 0.78 ± 0.13 (continuous scale, 0 = “none” → 1 = “excellent”). Mean level of motion artifacts was low, measuring 0.13 ± 0.08 (continuous scale, 0 = “none” → 1 = “severe”). Conclusion: It is feasible to perform single breathhold, noncardiac gated, ultrafast, high spatial‐temporal resolution whole chest MR pulmonary perfusion imaging in humans. J. Magn. Reson. Imaging 2013;38:751–756. © 2013 Wiley Periodicals, Inc.
constrained reconstruction DCE MRI HYCR HYPR IVD pulmonary perfusion

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