Journal article
Pure cannabidiol in the treatment of malignant migrating partial seizures in infancy: a case report
Pediatric neurology, Vol.52(5), pp.544-547
05/2015
DOI: 10.1016/j.pediatrneurol.2015.02.008
PMID: 25882081
Abstract
Malignant migrating partial seizures in infancy is a devastating pharmacoresistent epileptic encephalopathy of unknown etiology characterized by onset in the first 6 months of life, continuous migrating focal seizures with corresponding multifocal electroencephalographic discharges, developmental deterioration, and early mortality. Recent widespread interest in the nonpsychoactive component of the cannabis plant, cannabidiol, as a potential treatment for refractory devastating epilepsies has led to individual trials initiated by families or physicians in states that have legalized medical marijuana with anecdotal success.
We describe a now 10-month-old boy with malignant migrating partial seizures in infancy who made developmental gains and demonstrated sustained seizure reduction with the addition of cannabidiol to his antiepileptic regimen.
This report supports a role for cannabidiol in the treatment of malignant migrating partial seizures in infancy.
Details
- Title: Subtitle
- Pure cannabidiol in the treatment of malignant migrating partial seizures in infancy: a case report
- Creators
- Dimah Saade - University of Iowa Stead Family Children’s HospitalCharuta Joshi - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Pediatric neurology, Vol.52(5), pp.544-547
- DOI
- 10.1016/j.pediatrneurol.2015.02.008
- PMID
- 25882081
- NLM abbreviation
- Pediatr Neurol
- ISSN
- 0887-8994
- eISSN
- 1873-5150
- Language
- English
- Date published
- 05/2015
- Academic Unit
- Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Neurology (Pediatrics)
- Record Identifier
- 9984353937302771
Metrics
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