Journal article
Purification of streptococcal pyrogenic exotoxin a
Methods in molecular medicine, Vol.36, pp.59-66
2000
DOI: 10.1385/1-59259-216-3:59
PMID: 21340964
Abstract
Group A streptococci secrete a variety of molecules, many of which are recognized as virulence factors important in the establishment of streptococcal infections. Among these extracellular products is streptococcal pyrogenic exotoxin A (SPE A, scarlet fever toxin A, erythrogenic toxin A) (1). Other SPEs include toxin serotypes B and C (1), streptococcal superantigen (SSA) (2), and SPE F (mitogenic factor) (3,4). Combinations of these toxins are believed to be important in streptococcal toxic shock syndrome. The latter two molecules will not be discussed in this chapter, but methods utilized to purify SPEs A-C also may be used to purify SSA and SPE F.
Details
- Title: Subtitle
- Purification of streptococcal pyrogenic exotoxin a
- Creators
- M Roggiani - Department of Medicine, Division of Infectious Disease, Kansas University Medical Center, Kansas City, KSP M Schlievert
- Resource Type
- Journal article
- Publication Details
- Methods in molecular medicine, Vol.36, pp.59-66
- Publisher
- United States
- DOI
- 10.1385/1-59259-216-3:59
- PMID
- 21340964
- ISSN
- 1543-1894
- eISSN
- 1940-6037
- Language
- English
- Date published
- 2000
- Academic Unit
- Microbiology and Immunology; Internal Medicine
- Record Identifier
- 9984001130902771
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