Journal article
QT prolongation and polymorphous ventricular tachycardia associated with trasodone-amiodarone combination
International journal of cardiology, Vol.52(1), pp.27-29
1995
DOI: 10.1016/0167-5273(95)02435-Y
PMID: 8707432
Abstract
Trasodone, a second generation antidepressant, has been shown to equal standard tricyclics in clinical efficacy while causing significantly fewer cardiac side effects. Although clinical trials have demonstrated a relatively safe arrhythmogenic profile, trasodone has been implicated in the pathogenesis of ventricular arrhythmias. This report describes a patient in whom the administration of trasodone in addition to previously well-tolerated long-term amiodarone therapy was associated with a marked prolongation of the QT interval and polymorphous ventricular tachycardia. Caution in the concurrent use of trasodone and other medications known to cause QT prolongation and polymorphous ventricular tachycardia is recommended.
Details
- Title: Subtitle
- QT prolongation and polymorphous ventricular tachycardia associated with trasodone-amiodarone combination
- Creators
- Alexander Mazur - Department of Cardiology, Beilinson Medical Center, Petah Tiqva, IsraelBoris Strasberg - Department of Cardiology, Beilinson Medical Center, Petah Tiqva, IsraelJairo Kusniec - Department of Cardiology, Beilinson Medical Center, Petah Tiqva, IsraelSamuel Sclarovsky - Department of Cardiology, Beilinson Medical Center, Petah Tiqva, Israel
- Resource Type
- Journal article
- Publication Details
- International journal of cardiology, Vol.52(1), pp.27-29
- DOI
- 10.1016/0167-5273(95)02435-Y
- PMID
- 8707432
- NLM abbreviation
- Int J Cardiol
- ISSN
- 0167-5273
- eISSN
- 1874-1754
- Publisher
- Elsevier Ireland Ltd
- Language
- English
- Date published
- 1995
- Academic Unit
- Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984094676302771
Metrics
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