Quantification of the Roles of Trabecular Microarchitecture and Trabecular Type in Determining the Elastic Modulus of Human Trabecular Bone

Xiaowei S Liu; Paul Sajda; Punam K Saha; Felix W Wehrli; X Edward Guo

doi:10.1359/jbmr.060716

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Quantification of the Roles of Trabecular Microarchitecture and Trabecular Type in Determining the Elastic Modulus of Human Trabecular Bone

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Quantification of the Roles of Trabecular Microarchitecture and Trabecular Type in Determining the Elastic Modulus of Human Trabecular Bone

Xiaowei S Liu, Paul Sajda, Punam K Saha, Felix W Wehrli and X Edward Guo

Journal of bone and mineral research, Vol.21(10), pp.1608-1617

10/2006

DOI: 10.1359/jbmr.060716

PMCID: PMC3225012

PMID: 16995816

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Abstract

The roles of microarchitecture and types of trabeculae in determining elastic modulus of trabecular bone have been studied in μCT images of 29 trabecular bone samples by comparing their Young’s moduli calculated by finite element analysis (FEA) with different trabecular type-specific reconstructions. The results suggest that trabecular plates play an essential role in determining elastic properties of trabecular bone.

Osteoporosis

μCT imaging

trabecular type

digital topology

microarchitecture

Details

Title: Subtitle: Quantification of the Roles of Trabecular Microarchitecture and Trabecular Type in Determining the Elastic Modulus of Human Trabecular Bone
Creators: Xiaowei S Liu - Bone Bioengineering Laboratory, Department of Biomedical Engineering, Columbia University, New York, New York, USA
Paul Sajda - Laboratory for Intelligent Imaging and Neural Computing, Department of Biomedical Engineering, Columbia University, New York, New York, USA
Punam K Saha - Laboratory for Structural NMR Imaging, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Felix W Wehrli - Laboratory for Structural NMR Imaging, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
X Edward Guo - Bone Bioengineering Laboratory, Department of Biomedical Engineering, Columbia University, New York, New York, USA
Resource Type: Journal article
Publication Details: Journal of bone and mineral research, Vol.21(10), pp.1608-1617
DOI: 10.1359/jbmr.060716
PMID: 16995816
PMCID: PMC3225012
ISSN: 0884-0431
eISSN: 1523-4681
Grant note: R01 AR051376-01A1 || AR / National Institute of Arthritis and Musculoskeletal and Skin Diseases : NIAMS
Language: English
Date published: 10/2006
Academic Unit: Radiology; Electrical and Computer Engineering
Record Identifier: 9984051980002771

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