Quantification of thoracic volumes by three-dimensional imaging

Sebastian Krayer; Kai Rehder; Kenneth C Beck; Peter D Cameron; Edward P Didier; Eric A Hoffman

doi:10.1152/jappl.1987.62.2.591

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Quantification of thoracic volumes by three-dimensional imaging

Journal article

Peer reviewed

Quantification of thoracic volumes by three-dimensional imaging

Sebastian Krayer, Kai Rehder, Kenneth C Beck, Peter D Cameron, Edward P Didier and Eric A Hoffman

Journal of applied physiology (1985), Vol.62(2), pp.591-598

1987

DOI: 10.1152/jappl.1987.62.2.591

PMID: 3558218

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Abstract

End-expiratory thoracic cavity volume (Vthx) was measured in eight volunteers lying supine by three-dimensional X-ray computed tomography using the Dynamic Spatial Reconstructor. Untrapped end-expiratory pulmonary gas volume at functional residual capacity (FRC) was determined by nitrogen clearance. Both measurements were done before and after induction of anesthesia-paralysis. After induction of anesthesia-paralysis, Vthx and FRC were consistently and significantly (P < 0.01) reduced by 0.28 ± 0.22 (SD) and 0.59 ± 0.24 liter, respectively. The reduction of FRC was larger than the reduction of Vthx (ΔVthx) in six of the eight subjects, a finding suggesting that intrathoracic fluid (blood) plus trapped gas volume (Vtt) increased. Changes in Vthx were partitioned into volume changes from the thoracic rib cage (ΔVrc) and from shape and/or position changes of the diaphragm (ΔVdi). ΔVrc contributed significantly (0.17 ± 0.15 liter, P < 0.02) to ΔVthx, whereas ΔVdi contributed only in four of the eight subjects. We conclude that ΔVrc, ΔVdi, and ΔVtt contribute to the reduction of FRC after induction of anesthesia-paralysis in humans; the relative contribution of them varies among subjects.

Respiratory System

Biological and medical sciences

Investigative techniques, diagnostic techniques (general aspects)

Medical sciences

Radiodiagnosis. Nmr imagery. Nmr spectrometry

Details

Title: Subtitle: Quantification of thoracic volumes by three-dimensional imaging
Creators: Sebastian Krayer - Mayo clin., Rochester MN 55905, United States
Kai Rehder - Mayo clin., Rochester MN 55905, United States
Kenneth C Beck - Mayo clin., Rochester MN 55905, United States
Peter D Cameron - Mayo clin., Rochester MN 55905, United States
Edward P Didier - Mayo clin., Rochester MN 55905, United States
Eric A Hoffman - Mayo clin., Rochester MN 55905, United States
Resource Type: Journal article
Publication Details: Journal of applied physiology (1985), Vol.62(2), pp.591-598
DOI: 10.1152/jappl.1987.62.2.591
PMID: 3558218
NLM abbreviation: J Appl Physiol (1985)
ISSN: 8750-7587
eISSN: 1522-1601
Publisher: American Physiological Society
Language: English
Date published: 1987
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Radiology; Internal Medicine
Record Identifier: 9984318815802771

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