Journal article
Quantitative Measurement of Cortical Surface Features in Localization-Related Temporal Lobe Epilepsy
Neuropsychology, Vol.18(4), pp.729-737
10/2004
DOI: 10.1037/0894-4105.18.4.729
PMID: 15506841
Abstract
Differences in cortical surface features between healthy controls (n = 48) and patients with temporal lobe epilepsy (n = 46), ages 14-59, were characterized by means of advanced quantitative MRI processing techniques. Cortical surface features of interest included gyral and sulcal curvature, cortical depth, and total cortical surface area. Epilepsy patients and controls differed on measures of gyrification; the abnormalities generalized despite the focal nature of the primary epileptic process. Changes in cortical surface features were associated with increasing chronological age in both groups. Abnormalities in gyrification were associated with cognitive performance and with other morphometric measurements (e.g., surface cerebral spinal fluid). These findings are related to the literature regarding morphometric changes associated with temporal lobe epilepsy and normal aging.
Details
- Title: Subtitle
- Quantitative Measurement of Cortical Surface Features in Localization-Related Temporal Lobe Epilepsy
- Creators
- Temitayo Oyegbile - Department of Neurology, University of WisconsinRuss Hansen - Department of Neurology, University of WisconsinVincent Magnotta - Department of Psychiatry, University of IowaDan O'Leary - Department of Psychiatry, University of IowaBrian Bell - Department of Neurology, University of WisconsinMichael Seidenberg - Department of Psychology, Rosalind Franklin University of Science and Medicine (formerly the Chicago Medical School)Bruce P Hermann - Department of Neurology, University of Wisconsin
- Contributors
- James T Becker (Editor)
- Resource Type
- Journal article
- Publication Details
- Neuropsychology, Vol.18(4), pp.729-737
- DOI
- 10.1037/0894-4105.18.4.729
- PMID
- 15506841
- NLM abbreviation
- Neuropsychology
- ISSN
- 0894-4105
- eISSN
- 1931-1559
- Publisher
- American Psychological Association
- Language
- English
- Date published
- 10/2004
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Psychiatry; Iowa Neuroscience Institute
- Record Identifier
- 9984003479702771
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