Journal article
Quantitative and regiocontrolled cross-photocycloaddition of the anticancer drug 5-fluorouracil achieved in a cocrystal
Chemical communications (Cambridge, England), Vol.52(89), pp.13109-13111
2016
DOI: 10.1039/C6CC06570H
PMID: 27759136
Abstract
We describe a [2+2] cross-photocycloaddition of the anticancer drug 5-fluorouracil in the solid state that proceeds regioselectively and in quantitative yield. The photocycloaddition occurs in a cocrystal with trans-2,2′-bis(pyridyl)ethylene.
Details
- Title: Subtitle
- Quantitative and regiocontrolled cross-photocycloaddition of the anticancer drug 5-fluorouracil achieved in a cocrystal
- Creators
- Andrew J. E Duncan - Department of Chemistry, University of Iowa, Iowa City, USARoxanne L Dudovitz - Department of Chemistry, University of Iowa, Iowa City, USAShawna J Dudovitz - Department of Chemistry, University of Iowa, Iowa City, USAJelena Stojaković - Department of Chemistry, University of Iowa, Iowa City, USAS. V. Santhana Mariappan - Central NMR Facility, University of Iowa, Iowa City, USALeonard R MacGillivray - Department of Chemistry, University of Iowa, Iowa City, USA
- Resource Type
- Journal article
- Publication Details
- Chemical communications (Cambridge, England), Vol.52(89), pp.13109-13111
- DOI
- 10.1039/C6CC06570H
- PMID
- 27759136
- NLM abbreviation
- Chem Commun (Camb)
- ISSN
- 1359-7345
- eISSN
- 1364-548X
- Publisher
- Royal Society of Chemistry
- Language
- English
- Date published
- 2016
- Academic Unit
- Pharmaceutical Sciences and Experimental Therapeutics; Chemistry
- Record Identifier
- 9984216576502771
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