Journal article
Quantitative assessment of blood inflow effects in functional MRI signals
Magnetic resonance in medicine, Vol.36(2), pp.314-319
08/1996
DOI: 10.1002/mrm.1910360219
PMID: 8843386
Abstract
Functional MRI (fMRI) signal dependence on changes in blood flow velocities were analyzed for both conventional and echo-planar (EPI) gradient-echo pulse sequences. As the flow velocity increases, the fMRI signal increases monotonically in spoiled gradient-echo sequences, while the fMRI signal may increase or decrease in conventional refocused gradient-echo sequences. A larger flip angle generates a larger inflow contribution to the fMRI signal. For conventional gradient-echo sequences, the inflow contribution to the fMRI images is dominated by the cortical draining veins, while its effect on capillaries is generally small and may be negligible in the spoiled sequences. For EPI gradient-echo sequences, the contribution from inflow effects is relatively small, as compared with the blood oxygen level-dependent (BOLD) contribution, to the fMRI signal, not only for capillaries but also for the cortical draining veins.
Details
- Title: Subtitle
- Quantitative assessment of blood inflow effects in functional MRI signals
- Creators
- Jia-Hong Gao - Research Imaging Center, The University of Texas Health Science Center, San Antonio, TexasIra Miller - Biomedical Sciences Corps, United States Air Force, Washington University School of Medicine, St. Louis, MissouriSong Lai - Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MissouriJinhu Xiong - Research Imaging Center, The University of Texas Health Science Center, San Antonio, TexasPeter T Fox - Research Imaging Center, The University of Texas Health Science Center, San Antonio, Texas
- Resource Type
- Journal article
- Publication Details
- Magnetic resonance in medicine, Vol.36(2), pp.314-319
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company
- DOI
- 10.1002/mrm.1910360219
- PMID
- 8843386
- ISSN
- 0740-3194
- eISSN
- 1522-2594
- Number of pages
- 6
- Language
- English
- Date published
- 08/1996
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering
- Record Identifier
- 9984083261202771
Metrics
21 Record Views