Racial differences in survival of oral and pharyngeal cancer patients in North Carolina

D J Caplan; I Hertz-Picciotto

doi:10.1111/j.1752-7325.1998.tb02988.x

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Racial differences in survival of oral and pharyngeal cancer patients in North Carolina

Journal article

Peer reviewed

Racial differences in survival of oral and pharyngeal cancer patients in North Carolina

D J Caplan and I Hertz-Picciotto

Journal of public health dentistry, Vol.58(1), pp.36-43

1998

DOI: 10.1111/j.1752-7325.1998.tb02988.x

PMID: 9608444

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Abstract

This study seeks to determine whether lower survival of black versus white oral and pharyngeal cancer patients is due to, or differs by, stage at diagnosis. Subjects identified through the North Carolina Central Cancer Registry included all black and white North Carolina residents diagnosed from 1987 to 1990 with malignant squamous cell carcinoma of the oral cavity or pharynx. Proportional hazards regression models were used to calculate hazard ratios for all-cause mortality during the first 18 months after diagnosis, adjusting for age, reported histologic grade, site, and several time-dependent interactions. Within the first two months after diagnosis, the black/white hazard ratio for mortality among those with localized disease was 11.8 (95% CI = 3.7, 37.5), compared to 6.4 (95% CI = 2.6, 15.8) for those with advanced disease. During months 3 to 18 after diagnosis, black/white hazard ratios were 2.07 (95% CI = 1.03, 4.18) among those with localized disease and 1.12 (95% CI = 0.85, 1.47) for those with advanced disease. In the first 18 months after diagnosis, blacks with oral and pharyngeal cancer have higher all-cause mortality than whites diagnosed at the same stage of disease. Racial differences are greater among those with localized disease than for those with more advanced conditions.

Residence Characteristics

Confidence Intervals

Age Factors

Follow-Up Studies

Carcinoma, Squamous Cell - pathology

Humans

Middle Aged

Male

Carcinoma, Squamous Cell - mortality

Aged, 80 and over

Adult

Female

Registries

North Carolina - epidemiology

Proportional Hazards Models

Hospitals, County

European Continental Ancestry Group

Survival Rate

Mouth Neoplasms - mortality

Pharyngeal Neoplasms - mortality

Adolescent

Sex Factors

Mouth Neoplasms - pathology

Pharyngeal Neoplasms - pathology

Aged

African Continental Ancestry Group

Neoplasm Staging

Details

Title: Subtitle: Racial differences in survival of oral and pharyngeal cancer patients in North Carolina
Creators: D J Caplan - Department of Dental Ecology, School of Dentistry, University of North Carolina, Chapel Hill 27599-7450, USA. dan_caplan@unc.edu
I Hertz-Picciotto
Resource Type: Journal article
Publication Details: Journal of public health dentistry, Vol.58(1), pp.36-43
Publisher: United States
DOI: 10.1111/j.1752-7325.1998.tb02988.x
PMID: 9608444
ISSN: 0022-4006
eISSN: 1752-7325
Grant note: 5T32DE07191-05 / NIDCR NIH HHS
Language: English
Date published: 1998
Academic Unit: Preventive and Community Dentistry
Record Identifier: 9983917669502771

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27 Times Cited - Web of Science