Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group

Dennis M Black; Steven R Cummings; David B Karpf; Jane A Cauley; Desmond E Thompson; Michael C Nevitt; Douglas C Bauer; Harry K Genant; William L Haskell; Robert Marcus; Susan M Ott; James C Torner; Sara A Quandt; Theodore F Reiss; Kristine E Ensrud

doi:10.1016/s0140-6736(96)07088-2

$Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group$

Journal article

Peer reviewed

Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group

Dennis M Black, Steven R Cummings, David B Karpf, Jane A Cauley, Desmond E Thompson, Michael C Nevitt, Douglas C Bauer, Harry K Genant, William L Haskell, Robert Marcus, …

The Lancet (British edition), Vol.348(9041), pp.1535-1541

12/07/1996

DOI: 10.1016/s0140-6736(96)07088-2

PMID: 8950879

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Abstract

Previous studies have shown that alendronate can increase bone mineral density (BMD) and prevent radiographically defined (morphometric) vertebral fractures. The Fracture Intervention Trial aimed to investigate the effect of alendronate on the risk of morphometric as well as clinically evident fractures in postmenopausal women with low bone mass.

Radiography

Follow-Up Studies

Humans

Middle Aged

Risk

Osteoporosis, Postmenopausal - drug therapy

Alendronate - therapeutic use

Spinal Fractures - diagnostic imaging

Femur Neck - diagnostic imaging

Spinal Fractures - prevention & control

Alendronate - adverse effects

Bone Density - drug effects

Hip Fractures - prevention & control

Spinal Fractures - complications

Aged, 80 and over

Hip Fractures - diagnostic imaging

Female

Aged

Fractures, Bone - diagnostic imaging

Femur Neck - drug effects

Fractures, Bone - prevention & control

Alendronate - administration & dosage

Details

Title: Subtitle: Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group
Creators: Dennis M Black - Department of Epidemiology and Biostatistics, University of California, San Francisco 94143, USA
Steven R Cummings
David B Karpf
Jane A Cauley
Desmond E Thompson
Michael C Nevitt
Douglas C Bauer
Harry K Genant
William L Haskell
Robert Marcus
Susan M Ott
James C Torner
Sara A Quandt
Theodore F Reiss
Kristine E Ensrud
Resource Type: Journal article
Publication Details: The Lancet (British edition), Vol.348(9041), pp.1535-1541
DOI: 10.1016/s0140-6736(96)07088-2
PMID: 8950879
NLM abbreviation: Lancet
ISSN: 0140-6736
eISSN: 1474-547X
Publisher: England
Language: English
Date published: 12/07/1996
Academic Unit: Epidemiology; Surgery; Injury Prevention Research Center; Neurosurgery
Record Identifier: 9983996071202771

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