Logo image
Ranitidine-Induced Cranial Dystonia
Journal article   Peer reviewed

Ranitidine-Induced Cranial Dystonia

Bradley J Davis, Edward A Aul, Mark A Granner and Robert L Rodnitzky
Clinical neuropharmacology, Vol.17(5), pp.489-491
10/1994
DOI: 10.1097/00002826-199410000-00015
PMID: 9316702

View Online

Abstract

We report a case of cranial dystonia related to the administration of ranitidine. The symptoms started shortly after institution of treatment, resolved after discontinuation, and recurred upon repeat administration of the drug. Although there have been a few reports of abnormal involuntary movements related to other histamine2 antagonists, this is only the second reported instance due to ranitidine and the first reported instance of dystonia related to the drug. The pathophysiology of this effect is unclear, but a central cholinergic effect of this agent may be a contributing factor.

Details

Metrics

Logo image