Rapid Prototyping Raw Models on the Basis of High Resolution Computed Tomography Lung Data for Respiratory Flow Dynamics

Frederik L Giesel; Amit Mehndiratta; Hendrik von Tengg-Kobligk; A Schaeffer; Kevin Teh; E.A Hoffman; Hans-Ulrich Kauczor; E.J.R van Beek; Jim M Wild

doi:10.1016/j.acra.2008.10.008

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Rapid Prototyping Raw Models on the Basis of High Resolution Computed Tomography Lung Data for Respiratory Flow Dynamics

Journal article

Peer reviewed

Rapid Prototyping Raw Models on the Basis of High Resolution Computed Tomography Lung Data for Respiratory Flow Dynamics

Frederik L Giesel, Amit Mehndiratta, Hendrik von Tengg-Kobligk, A Schaeffer, Kevin Teh, E.A Hoffman, Hans-Ulrich Kauczor, E.J.R van Beek and Jim M Wild

Academic radiology, Vol.16(4), pp.495-498

2009

DOI: 10.1016/j.acra.2008.10.008

PMID: 19268862

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Abstract

Three-dimensional image reconstruction by volume rendering and rapid prototyping has made it possible to visualize anatomic structures in three dimensions for interventional planning and academic research. Volumetric chest computed tomography was performed on a healthy volunteer. Computed tomographic images of the larger bronchial branches were segmented by an extended three-dimensional region-growing algorithm, converted into a stereolithography file, and used for computer-aided design on a laser sintering machine. The injection of gases for respiratory flow modeling and measurements using magnetic resonance imaging were done on a hollow cast. Manufacturing the rapid prototype took about 40 minutes and included the airway tree from trackea to segmental bronchi (fifth generation). The branching of the airways are clearly visible in the 3He images, and the radial imaging has the potential to elucidate the airway dimensions. The results for flow patterns in the human bronchial tree using the rapid-prototype model with hyperpolarized helium-3 magnetic resonance imaging show the value of this model for flow phantom studies.

Pediatrics

development

3D visualization

congenital malformation

ventricles

Details

Title: Subtitle: Rapid Prototyping Raw Models on the Basis of High Resolution Computed Tomography Lung Data for Respiratory Flow Dynamics
Creators: Frederik L Giesel
Amit Mehndiratta
Hendrik von Tengg-Kobligk
A Schaeffer
Kevin Teh
E.A Hoffman
Hans-Ulrich Kauczor
E.J.R van Beek
Jim M Wild
Resource Type: Journal article
Publication Details: Academic radiology, Vol.16(4), pp.495-498
Publisher: Elsevier Inc
DOI: 10.1016/j.acra.2008.10.008
PMID: 19268862
ISSN: 1076-6332
eISSN: 1878-4046
Language: English
Date published: 2009
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Radiology; Internal Medicine
Record Identifier: 9984051700402771

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