Rapid human immunodeficiency virus-1 testing on labor and delivery in 17 US hospitals: the MIRIAD experience

Denise J Jamieson; Mardge H Cohen; Robert Maupin; Steven Nesheim; Susan P Danner; Margaret A Lampe; Mary Jo O'Sullivan; Mayris P Webber; Jeffrey Wiener; Rosalind J Carter; Yvette Rivero; Mary Glenn Fowler; Marc Bulterys

doi:10.1016/j.ajog.2007.03.067

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Rapid human immunodeficiency virus-1 testing on labor and delivery in 17 US hospitals: the MIRIAD experience

Journal article

Open access

Peer reviewed

Rapid human immunodeficiency virus-1 testing on labor and delivery in 17 US hospitals: the MIRIAD experience

Denise J Jamieson, Mardge H Cohen, Robert Maupin, Steven Nesheim, Susan P Danner, Margaret A Lampe, Mary Jo O'Sullivan, Mayris P Webber, Jeffrey Wiener, Rosalind J Carter, …

American journal of obstetrics and gynecology, Vol.197(3 Suppl), pp.S72-S82

09/01/2007

DOI: 10.1016/j.ajog.2007.03.067

PMID: 17825653

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Abstract

The objective of the study was to evaluate the feasibility, acceptability, and accuracy of rapid human immunodeficiency virus (HIV) testing during labor. The Mother-Infant Rapid Intervention at Delivery (MIRIAD) study was a prospective, multicenter study that offered voluntary, rapid HIV testing to women with undocumented HIV status at 17 hospitals in 6 cities. Of 12,481 eligible women, 74% were approached for participation and 85.5% of those approached accepted rapid HIV testing. Among 7753 women tested, MIRIAD identified 52 (0.7%) HIV-infected women. The time between obtaining the blood sample for the rapid test and reporting the results to the health care provider was shorter for hospitals utilizing point-of-care testing than in hospitals utilizing laboratory-based testing (30 minutes vs 68 minutes; P < .0001), and point-of-care testing strategies were 14 times more likely to have a short turnaround as laboratory testing strategies. Routine rapid testing during labor provides a feasible, acceptable, and accurate way to identify HIV-infected women before delivery.

Adult

Clinical Laboratory Techniques

Delivery, Obstetric

Feasibility Studies

Female

HIV Infections - diagnosis

HIV-1

Hospitals

Humans

Immunoenzyme Techniques

Labor, Obstetric - blood

Point-of-Care Systems

Pregnancy

Prospective Studies

Time Factors

United States

Details

Title: Subtitle: Rapid human immunodeficiency virus-1 testing on labor and delivery in 17 US hospitals: the MIRIAD experience
Creators: Denise J Jamieson - National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention
Mardge H Cohen - John H. Stroger, Jr. Hospital of Cook County
Robert Maupin - Louisiana State University
Steven Nesheim - Emory University
Susan P Danner - National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention
Margaret A Lampe - National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention
Mary Jo O'Sullivan - University of Miami
Mayris P Webber - Albert Einstein College of Medicine
Jeffrey Wiener - Centers for Disease Control and Prevention
Rosalind J Carter - Albert Einstein College of Medicine
Yvette Rivero - University of Miami
Mary Glenn Fowler - MUJHU Research Collaboration
Marc Bulterys - National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention
Resource Type: Journal article
Publication Details: American journal of obstetrics and gynecology, Vol.197(3 Suppl), pp.S72-S82
DOI: 10.1016/j.ajog.2007.03.067
PMID: 17825653
NLM abbreviation: Am J Obstet Gynecol
ISSN: 0002-9378
eISSN: 1097-6868
Grant note: 417719 / PHS HHS 517715 / PHS HHS U64/217724 / PHS HHS 479935 / PHS HHS 617734 / PHS HHS
Language: English
Date published: 09/01/2007
Academic Unit: Obstetrics and Gynecology; VPMA - Administration
Record Identifier: 9984446448302771

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